ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Struktur
71997-40-5
CAS-Nr.
71997-40-5
Englisch Name:
ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
Synonyma:
oATP;Oxidized ATP trisodium salt;adenosine 5'-triphosphate-2',3'-dialdehyde;Adenosine 5′-triphosphate, periodate oxidized;Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem;ADENOSINE 5-TRIPHOSPHATE, PERIODATEOXIDI ZED SODIUM;ADENOSINE 5'-TRIPHOSPHATE-2', 3'-DIALDEHYDE SODIUM SALT;Adenosine 5`-triphosphate sodiuM salt periodate oxidized;ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
CBNumber:
CB3141054
Summenformel:
C10H13N5NaO13P3
Molgewicht:
527.15
MOL-Datei:
71997-40-5.mol

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Eigenschaften

storage temp. 
-20°C
Aggregatzustand
White powder
Farbe
White to off-white

Sicherheit

WGK Germany  3

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
  • as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
  • as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
  • to evaluate the physiological significance of elevated intracellular ATP levels
  • increased?P2rx7?expression for osteoclastogenesis in?Flcn-deficient cells

Allgemeine Beschreibung

A 2′,3′-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes. Acts as a specific, irreversible antagonist of P2Z/P2X7 purinergic receptors in J774 mouse macrophages. Does not affect P2γ receptors. Inhibits inflammatory pain in arthritic rat model by blocking ATP action on P2X7 receptor in nerve terminals. Also shown to irreversibly block ATP-induced Ca2+ influx in lymphocytes (?100 μM). O-ATP-treated mice display better preservation and lower rate of rejection of pancreatic islet grafts with reduced Th1 transcripts.

Biochem/physiol Actions

Reversible: no

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52925 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19863 58
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771
sales@heowns.com China 14435 57
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24648 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757
359382369@qq.com China 10674 58
Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836
1986399151@qq.com China 9844 58

71997-40-5()Verwandte Suche:


  • ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
  • ADENOSINE 5'-TRIPHOSPHATE-2', 3'-DIALDEHYDE SODIUM SALT
  • oATP
  • ADENOSINE 5-TRIPHOSPHATE, PERIODATEOXIDI ZED SODIUM
  • adenosine 5'-triphosphate-2',3'-dialdehyde
  • Adenosine 5`-triphosphate sodiuM salt periodate oxidized
  • Adenosine 5′-triphosphate, periodate oxidized
  • Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem
  • Oxidized ATP trisodium salt
  • 71997-40-5
  • C10H14N5O13P3
  • C10H13N5NaO13P3
  • Nucleotides
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical
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