CAY10607

CAY10607 Struktur
1012788-65-6
CAS-Nr.
1012788-65-6
Englisch Name:
CAY10607
Synonyma:
CAY10607;HSP90-IN-29;CAY10607 Exclusive;Benzisoxazole Hsp90 Inhibitor;1,3-Benzenediol, 4-chloro-6-[5-[[2-(4-morpholinyl)ethyl]amino]-1,2-benzisoxazol-3-yl]-
CBNumber:
CB52590441
Summenformel:
C19H20ClN3O4
Molgewicht:
389.83
MOL-Datei:
1012788-65-6.mol

CAY10607 Eigenschaften

storage temp. 
Store at -20°C
Löslichkeit
DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
Aggregatzustand
A crystalline solid

Sicherheit

CAY10607 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Benzisoxazole Hsp90 inhibitor is an inhibitor of heat shock protein 90 (Hsp90; IC50 = 30 nM in a fluorescence polarization assay). It is selective for Hsp90 over a panel of kinases (IC50s = >20 μM). Benzisoxazole Hsp90 inhibitor inhibits the proliferation of HCT116, SK-BR-3, LNCaP, DU145, and H157 cancer cells (IC50s = 0.28, 0.37, 0.17, 0.29, and 0.23 μM, respectively). It also induces degradation of the Hsp90 targets HER2 and the androgen receptor in SK-BR-3 and LNCaP cells, respectively, with an IC50 value of 0.33 μM for both.

CAY10607 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CAY10607 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 21)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alfa Chemistry

Info@alfa-chemistry.com United States 24072 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44844 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337
3427709316@qq.com China 7979 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11975 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 19696 58

  • CAY10607
  • Benzisoxazole Hsp90 Inhibitor
  • CAY10607 Exclusive
  • 1,3-Benzenediol, 4-chloro-6-[5-[[2-(4-morpholinyl)ethyl]amino]-1,2-benzisoxazol-3-yl]-
  • HSP90-IN-29
  • 1012788-65-6
Copyright 2019 © ChemicalBook. All rights reserved