Sovilnesib Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Sovilnesib (AMG 650) is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.
in vitro
Sovilnesib is a kinesin-like protein KIF18A inhibitor.
in vivo
Sovilnesib (AMG 650; 10-100 mg/kg; p.o. daily, for 45 d; female nude mice without thymus with OVCAR-3 xenografts) inhibits tumor growth, Lasting tumor regression and cure occurred in 50% of the animals, Sovilnesib has no apparent toxicity.
Sovilnesib Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte