SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT

98672-91-4

CAS-Nr.: 98672-91-4

Englisch Name:: SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT

Synonyma:: BMS-18290;RJNDVCNWVBWHLY-BHQIHCQQSA-N;SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT;1S-[1α,2β(5Z),3β,4α]]-7-[3-[2-(Phenylcarbamoyl)hydrazinomethyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid;(Z)-7-[(1R,4S)-3α-[[2-[(Phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]heptan-2α-yl]-5-heptenoic acid;1S-[1α,2α(Z),3α,4α]]-7-[3-[[2-[(phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoicacid;5-Heptenoic acid, 7-[(1S,2R,3R,4R)-3-[[2-[(phenylamino)carbonyl]hydrazinyl]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)-

CBNumber:: CB8504564

Summenformel:: C21H29N3O4

Molgewicht:: 387.47

MOL-Datei:: 98672-91-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 9

SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT Eigenschaften

Schmelzpunkt:: 92-95 °C

Dichte: 1?+-.0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: ≤0.9mg/ml in ethanol;5mg/ml in DMSO;0.14mg/ml in dimethyl formamide

Aggregatzustand: White to off-white crystalline powder.

pka: 4.76±0.10(Predicted)

Farbe: White to off-white

Sicherheit

SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SQ 29,548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a K_i of 4.1 nM. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC₅₀ of 0.06 μM. It antagonizes U-46619 induced contraction of rat and guinea pig tracheal, arterial, and venous smooth muscles with drug/receptor dissociation constants (K_B) in the range of 0.5-1.7 nM. SQ 29,548 also inhibits the contraction of rat vascular smooth muscle induced by 8-iso PGF_2α.

Verwenden

SQ-29548 is a potent and selective thromboxane A2 receptor antagonist.

SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 9)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

SQ 29,548 (POTENT AND SPECIFIC THROMBOXA NE A2 RECEPT
(Z)-7-[(1R,4S)-3α-[[2-[(Phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]heptan-2α-yl]-5-heptenoic acid
BMS-18290
1S-[1α,2β(5Z),3β,4α]]-7-[3-[2-(Phenylcarbamoyl)hydrazinomethyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid
RJNDVCNWVBWHLY-BHQIHCQQSA-N
5-Heptenoic acid, 7-[(1S,2R,3R,4R)-3-[[2-[(phenylamino)carbonyl]hydrazinyl]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)-
1S-[1α,2α(Z),3α,4α]]-7-[3-[[2-[(phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoicacid
98672-91-4