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Lawesson Reagent

CAS No.
19172-47-5
Chemical Name:
Lawesson Reagent
Synonyms
LAWESSON REAGENT;LR;242-855-4;Lawesson's;Lawesson`s reagentsulfide dimer;2,4-BIS(4-METHOXYPHENYL)-2,4-DITHIOXO-1,3,2,4-DITHIADIPHOSPHETANE;2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE-2,4-DISULFIDE;2,4-BIS(4-METHOXYPHENYL)-1,3-DITHIA-2,4-DIPHOSPHETANE-2,4-DISULFIDE;AURORA KA-1707;awesson's Reag
CBNumber:
CB00125059
Molecular Formula:
C14H14O2P2S4
Molecular Weight:
404.47
MDL Number:
MFCD00005171
MOL File:
19172-47-5.mol
MSDS File:
SDS
Last updated:2024-08-07 10:42:15

Lawesson Reagent Properties

Melting point 228-230 °C(lit.)
Boiling point 525.8±60.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly)
form Powder
color White to almost white
Water Solubility Decomposition
Sensitive Moisture Sensitive
Merck 14,5391
BRN 1024888
InChI InChI=1S/C14H14O2P2S4/c1-15-11-3-7-13(8-4-11)17(19)21-18(20,22-17)14-9-5-12(16-2)6-10-14/h3-10H,1-2H3
InChIKey CFHGBZLNZZVTAY-UHFFFAOYSA-N
SMILES S1P(=S)(C2=CC=C(OC)C=C2)SP1(=S)C1=CC=C(OC)C=C1
CAS DataBase Reference 19172-47-5(CAS DataBase Reference)
FDA UNII A4125MQ8RX
EPA Substance Registry System 1,3,2,4-Dithiadiphosphetane, 2,4-bis(4-methoxyphenyl)-, 2,4-disulfide (19172-47-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
Hazard statements  H261
Precautionary statements  P231+P232-P422
Hazard Codes  Xn-F,Xi,Xn,F
Risk Statements  20/21/22-15/29-37
Safety Statements  8-43-36/37-22-38-7/8
RIDADR  3278
WGK Germany  3
13-21
TSCA  Yes
HazardClass  4.3
PackingGroup  III
HS Code  29349990
NFPA 704
2
2 1
W

Lawesson Reagent price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 227439 Lawesson reagent 97% 19172-47-5 10g $46.8 2024-03-01 Buy
Sigma-Aldrich 227439 Lawesson reagent 97% 19172-47-5 25g $57.2 2024-03-01 Buy
TCI Chemical B1133 Lawesson's Reagent [Sulfurating Reagent] >95.0%(T) 19172-47-5 25g $40 2024-03-01 Buy
TCI Chemical B1133 Lawesson's Reagent [Sulfurating Reagent] >95.0%(T) 19172-47-5 250g $242 2024-03-01 Buy
Alfa Aesar A14530 Lawesson's Reagent, 97% 19172-47-5 5g $19 2024-03-01 Buy
Product number Packaging Price Buy
227439 10g $46.8 Buy
227439 25g $57.2 Buy
B1133 25g $40 Buy
B1133 250g $242 Buy
A14530 5g $19 Buy

Lawesson Reagent Chemical Properties,Uses,Production

Description

Lawesson's reagent is a thiation agent used to convert carbonyl compounds into thiocarbonyls. It is also used to thionate enones, esters, lactones, amides, lactams and quinones. Further, it is used to prepare thiols from alcohols. It is associated with silver perchlorate and utilized as and oxophilic Lewis acid catalyst for Diels-Alder reaction of dienes with alfa, beta-unsaturated aldehydes.

Uses

Lawesson Reagent was mainly used in the thionation of various types of carbonyl groups, but nowadays it is also used in the construction of valuable heterocycles, important coupling reactions, and the decoration of metal-based attractive cores. Lawesson Reagent can convert an oxygen atom to a sulphur atom in a ketone, aldehyde, ester, amide, lactones, lactams, and quinones. Ketones, amides, and lactams react faster than corresponding esters. 

Reaction mechanism

Lawesson’s reagent is in equilibrium with reactive intermediate 2 (dithiophosphine ylide). This ylide then reacts with the carbonyl group to form thiaoxaphosphetane intermediate 3, which is further decomposed by a cycloelimination mechanism as a Wittig-analogous reaction.

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Global( 365)Suppliers
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Chongqing Chemdad Co., Ltd
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career henan chemical co
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View Lastest Price from Lawesson Reagent manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Burgess reagent pictures 2024-01-14 Burgess reagent
29684-56-8
US $5.00-0.50 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Lawesson 2021-07-02 Lawesson"s Reagent
19172-47-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
EATON'S REAGENT pictures 2019-07-12 EATON'S REAGENT
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US $1.00 / KG 1KG 99% 25kg Career Henan Chemical Co
  • Burgess reagent pictures
  • Burgess reagent
    29684-56-8
  • US $5.00-0.50 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Lawesson
  • Lawesson"s Reagent
    19172-47-5
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
AURORA KA-1707 4-METHOXYPHENYLTHIOPHOSPHORIC CYCLIC DI(THIOANHYDRIDE) 2,4-DI(4-METHOXYPHENYL)-1,3,2LAMBDA-5,4LAMBDA-5-DITHIADIPHOSPHETANE-2,4-DITHIONE P-METHOXYPHENYLTHIONOPHOSPHINE SULFIDE DIMER P-METHOXYPHENYLTHIOPHOSPHINE SULFIDE, DIMER 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulphide 2,4-Bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide Lawesson's Reagent [Sulfurating Reagent] 4-methoxyphenylthionophosphine sulfide dimer 2,4-Bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphosphetane 97% 4-Methoxyphenylthiophosphoric cyclic di(thioanhydride), LR, 2,4-Bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphosphetane, 2,4-Bis-(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide Lawesson's Reagent ,99% 1,3-Bis(4-methoxyphenyl)-2,4-dithia-1,3-diphospha(V)cyclobutane-1,3-dithione 2,4-Bis(4-methoxyphenyl)-1,3-dithia-2,4-diphospha(V)cyclobutane-2,4-dithione 2,4-Bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphacyclobutane-2,4-dithione 2,4-Bis(p-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-dithione 2,4-Bisthiolato-2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphospha(V)cyclobutane-2,4-diylium 2,4-Di(4-methoxyphenyl) -1,3,2lambda~5~,4lambda~5~-dithiadiphosphetane-2, 4-dithione (Lawesson's Reagent) Lawesson reagent ,98% Lawesson reagent ,99% Lawesson Reagent, 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulphide bis(4-Methoxyphenyl)-1,3,2$l^{5},4$l^{5}-dithiadiphosphetane-2,4-dithione 2,4-BIS(4-METHOXYPHENYL)-2,4-DITHIOXO-1 Lawesson reagent 97% 1,3,2,4-dithiadiphosphetane,2,4-bis(4-methoxyphenyl)-,2,4-disulfide LAWESSON'S REAGENT awesson's Reag p-Methoxyphenylthionophosphine sulfide 2,4-bis(4-methoxyphenyl)-2,4-bis(sulfanylidene)-1,3,2$l^{5},4$l^{5}-dithiadiphosphetane LAWESSON'S REAGENT For Synthesis 2,4-bis(4-methoxyphenyl)-2,4-bis(sulfanylidene)-1,3,2 Lawesson'sReagent(LR) Lawesson's Reagent ISO 9001:2015 REACH Lawesson'sReagen awesson's Reagent Lawessons Reagent,>98% Lawesson's Reagent [Sulfurating Reagent]> 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE-2 2,4-bis(4-methoxyphenyl)-2,4-disulfanylene-1,3,2,4-dithiadiphosphetane 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE-2,4-DISULFIDE 2,4-BIS(4-METHOXYPHENYL)-1,3-DITHIA-2,4-DIPHOSPHETANE-2,4-DISULFIDE 2,4-BIS(4-METHOXYPHENYL)-2,4-DITHIOXO-1,3,2,4-DITHIADIPHOSPHETANE Lawesson's Lawesson`s reagentsulfide dimer LR LAWESSON REAGENT 242-855-4 Lawson’s Reagent Lawesson's Reagent bis(4-methoxyphenyl)-1,3,2lambda5,4lambda5-dithiadiphosphetane-2,4-dithione 19172-47-5 1972-47-5 C14H14O2P2S4 C14H14O2P2S2 Sulfur Compounds (for Synthesis) Dithietanes Simple 4-Membered Ring Compounds Synthetic Reagents