Lawesson Reagent
- CAS No.
- 19172-47-5
- Chemical Name:
- Lawesson Reagent
- Synonyms
- LAWESSON REAGENT;LR;242-855-4;Lawesson's;Lawesson`s reagentsulfide dimer;2,4-BIS(4-METHOXYPHENYL)-2,4-DITHIOXO-1,3,2,4-DITHIADIPHOSPHETANE;2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE-2,4-DISULFIDE;2,4-BIS(4-METHOXYPHENYL)-1,3-DITHIA-2,4-DIPHOSPHETANE-2,4-DISULFIDE;AURORA KA-1707;awesson's Reag
- CBNumber:
- CB00125059
- Molecular Formula:
- C14H14O2P2S4
- Molecular Weight:
- 404.47
- MDL Number:
- MFCD00005171
- MOL File:
- 19172-47-5.mol
- MSDS File:
- SDS
Melting point | 228-230 °C(lit.) |
---|---|
Boiling point | 525.8±60.0 °C(Predicted) |
Density | 1.48±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform (Slightly) |
form | Powder |
color | White to almost white |
Water Solubility | Decomposition |
Sensitive | Moisture Sensitive |
Merck | 14,5391 |
BRN | 1024888 |
InChI | InChI=1S/C14H14O2P2S4/c1-15-11-3-7-13(8-4-11)17(19)21-18(20,22-17)14-9-5-12(16-2)6-10-14/h3-10H,1-2H3 |
InChIKey | CFHGBZLNZZVTAY-UHFFFAOYSA-N |
SMILES | S1P(=S)(C2=CC=C(OC)C=C2)SP1(=S)C1=CC=C(OC)C=C1 |
CAS DataBase Reference | 19172-47-5(CAS DataBase Reference) |
FDA UNII | A4125MQ8RX |
EPA Substance Registry System | 1,3,2,4-Dithiadiphosphetane, 2,4-bis(4-methoxyphenyl)-, 2,4-disulfide (19172-47-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H261 | |||||||||
Precautionary statements | P231+P232-P422 | |||||||||
Hazard Codes | Xn-F,Xi,Xn,F | |||||||||
Risk Statements | 20/21/22-15/29-37 | |||||||||
Safety Statements | 8-43-36/37-22-38-7/8 | |||||||||
RIDADR | 3278 | |||||||||
WGK Germany | 3 | |||||||||
F | 13-21 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 4.3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
Lawesson Reagent price More Price(32)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 227439 | Lawesson reagent 97% | 19172-47-5 | 10g | $46.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 227439 | Lawesson reagent 97% | 19172-47-5 | 25g | $57.2 | 2024-03-01 | Buy |
TCI Chemical | B1133 | Lawesson's Reagent [Sulfurating Reagent] >95.0%(T) | 19172-47-5 | 25g | $40 | 2024-03-01 | Buy |
TCI Chemical | B1133 | Lawesson's Reagent [Sulfurating Reagent] >95.0%(T) | 19172-47-5 | 250g | $242 | 2024-03-01 | Buy |
Alfa Aesar | A14530 | Lawesson's Reagent, 97% | 19172-47-5 | 5g | $19 | 2024-03-01 | Buy |
Lawesson Reagent Chemical Properties,Uses,Production
Description
Lawesson's reagent is a thiation agent used to convert carbonyl compounds into thiocarbonyls. It is also used to thionate enones, esters, lactones, amides, lactams and quinones. Further, it is used to prepare thiols from alcohols. It is associated with silver perchlorate and utilized as and oxophilic Lewis acid catalyst for Diels-Alder reaction of dienes with alfa, beta-unsaturated aldehydes.
Uses
Lawesson Reagent was mainly used in the thionation of various types of carbonyl groups, but nowadays it is also used in the construction of valuable heterocycles, important coupling reactions, and the decoration of metal-based attractive cores. Lawesson Reagent can convert an oxygen atom to a sulphur atom in a ketone, aldehyde, ester, amide, lactones, lactams, and quinones. Ketones, amides, and lactams react faster than corresponding esters.
Reaction mechanism
Lawesson’s reagent is in equilibrium with reactive intermediate 2 (dithiophosphine ylide). This ylide then reacts with the carbonyl group to form thiaoxaphosphetane intermediate 3, which is further decomposed by a cycloelimination mechanism as a Wittig-analogous reaction.
Lawesson Reagent Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 1243 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
Related articles
- Lawesson's Reagent – a widely used agent in Organic Syntheses
- Lawesson's reagent, or LR, is a chemical compound used in organic synthesis as a thiation agent. Its chemical formula is C14H1....
- Nov 25,2019
View Lastest Price from Lawesson Reagent manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-01-14 | Burgess reagent
29684-56-8
|
US $5.00-0.50 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2021-07-02 | Lawesson"s Reagent
19172-47-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2019-07-12 | EATON'S REAGENT
39394-84-8
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
- Burgess reagent
29684-56-8
- US $5.00-0.50 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- Lawesson"s Reagent
19172-47-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- EATON'S REAGENT
39394-84-8
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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