Acid Folic
- CAS No.
- 59-30-3
- Chemical Name:
- Acid Folic
- Synonyms
- PGA;Folate;Vitamin B;folic;Vitamin B11;PTEROYLMONOGLUTAMIC ACID;PTEROYLGLUTAMIC ACID;FOLIC ACID HYDRATE;PTEGLU;FOLACIN
- CBNumber:
- CB00128689
- Molecular Formula:
- C19H19N7O6
- Molecular Weight:
- 441.4
- MDL Number:
- MFCD00079305
- MOL File:
- 59-30-3.mol
- MSDS File:
- SDS
Melting point | 250 °C |
---|---|
alpha | 20 º (c=1, 0.1N NaOH) |
Boiling point | 552.35°C (rough estimate) |
Density | 1.4704 (rough estimate) |
refractive index | 1.6800 (estimate) |
storage temp. | 2-8°C |
solubility | boiling water: soluble1% |
form | Crystalline Powder |
pka | pKa 2.5 (Uncertain) |
color | Yellow to orange |
Odor | Odorless |
PH Range | 4 |
Water Solubility | 1.6 mg/L (25 ºC) |
Merck | 14,4221 |
BRN | 100781 |
BCS Class | 3 |
Stability | Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive. |
InChIKey | OVBPIULPVIDEAO-LBPRGKRZSA-N |
LogP | -0.990 (est) |
FDA 21 CFR | 172.345; 102.23; 104.20; 310.545 |
Substances Added to Food (formerly EAFUS) | FOLIC ACID |
CAS DataBase Reference | 59-30-3(CAS DataBase Reference) |
EWG's Food Scores | 1 |
NCI Dictionary of Cancer Terms | folate; folic acid |
FDA UNII | 935E97BOY8 |
NIST Chemistry Reference | Folic acid(59-30-3) |
NCI Drug Dictionary | folic acid |
ATC code | B03BB01,B03BB51,V04CX02 |
EPA Substance Registry System | L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (59-30-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Risk Statements | 33-62-68 |
Safety Statements | 24/25 |
WGK Germany | 1 |
RTECS | LP5425000 |
F | 8 |
TSCA | Yes |
HS Code | 29362900 |
Toxicity | A water soluble vitamin required in the diet of mammals. Sulfonamide drugs are selectively toxic to bacteria because they inhibit the incorporation of p-aminobenzoic acid into folic acid, a biosynthetic process in bacteria. Folic acid deficiency adversely affects prenatal development in humans. Dietary supplementation with folic acid dramatically reduces the incidence of neural tube defects in humans. Folic acid deficiency may also contribute to the causes of megaloblastic macrocytic anemia and a consequence of this is that this disease can be induced, as a side effect, when methotrexate, a folic acid antagonist, is used in cancer chemotherapy |
Acid Folic price More Price(55)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | F7876 | Folic acid ≥97% | 59-30-3 | 1g | $23.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 1286005 | Folic acid United States Pharmacopeia (USP) Reference Standard | 59-30-3 | 500mg | $447 | 2024-03-01 | Buy |
Sigma-Aldrich | BP937 | Folic acid British Pharmacopoeia (BP) Reference Standard | 59-30-3 | 150MG | $266 | 2023-06-20 | Buy |
TCI Chemical | F0043 | Folic Acid Hydrate >98.0%(HPLC)(T) | 59-30-3 | 25g | $65 | 2024-03-01 | Buy |
Alfa Aesar | J60833 | Folic acid, crystalline | 59-30-3 | 25g | $80.2 | 2024-03-01 | Buy |
Acid Folic Chemical Properties,Uses,Production
Description
Acid Folic is an essential B vitamin. It is converted to folate in vivo, which is a necessary cofactor for a variety of biological processes, including nucleotide synthesis and, thus, DNA synthesis and repair, among others. A deficiency in dietary acid folic can lead to a range of developmental and cognitive disorders, most prominently neural tube defects and congenital heart defects.
Chemical Properties
Acid solutions of Acid Folic are sensitive to heat, but towards neutrality, stability progressively increases. Solutions are inactivated by ultraviolet light and alkaline solutions are sensitive to oxidation. Acid Folic is also inactivated by light. It is incompatible with oxidizing agents, reducing agents and heavy metal ions.
Uses
Acid folic is generally used as an emollient. In vitro and in vivo skin studies now indicate its capacity to aid in DnA synthesis and repair, promote cellular turnover, reduce wrinkles, and promote skin firmness. There is some indication that acid folic may also protect DnA from uV-induced damage. Acid folic is a member of the vitamin B complex and is naturally occurring in leafy greens.
Side effects
The symptoms of a drug allergy include one or more of the following:
Swollen face/eyes/lips/tongue
Difficulty in breathing
Itchy skin rashes over your whole body
Physiological effects
Acid Folic is a type of vitamin naturally found in some foods that helps the body to produce red blood cells. A lack of folic acid may result in folate-deficiency anemia, a condition in which there is insufficient healthy red blood cells to provide oxygen to the body.
Acid Folic deficiency
Some symptoms of folate deficiency include:Trusted Source
weakness
fatigue
trouble concentrating
headache
irritability
heart palpitations
sores on the tongue and inside the mouth
a change in color of the skin, hair, or fingernails
irritability, headache, heart palpitations, and shortness of breath
Toxicity
Acid Folic is extremely rare to reach a toxic level when eating folate from food sources. In this case, if high acid folic intake continues to “hide”the symptoms of B12 deficiency for a long time, a slow but irreversible damage to the brain and nervous system may occur.
Acid Folic Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hengshui Haoye Co.,Ltd. | +86-2102300 +86-18632882519 | hy@haoyecom.cn | China | 365 | 58 |
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 158 | 58 |
XI AN SGONEK BIOLOGICAL TECHNOLOGY CO., LTD | 15202951039 | jason@sgonekbio.com | China | 268 | 58 |
Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 656 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 12272 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3878 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12495 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
Across Biotech Jinan Co LTD | +8613031735486 | frank@acrossbiotech.com | China | 105 | 58 |
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View Lastest Price from Acid Folic manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-10 | Folic acid
59-30-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-02-05 | Folic acid
59-30-3
|
US $1.00 / Kg/Bag | 1g/Bag | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. |
- Folic acid
59-30-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- Folic acid
59-30-3
- US $1.00 / Kg/Bag
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.