ChemicalBook >> CAS DataBase List >>Hyoscine Butylbromide
Hyoscine Butylbromide
- CAS No.
- 149-64-4
- Chemical Name:
- Hyoscine Butylbromide
- Synonyms
- HYOSCINE BUTYLBROMIDE;buscopan;HYOSCINE N-BUTYL BROMIDE;(1S,2R,4S,5S)-9-butyl-7-[(3-hydroxy-2-phenylpropanoyl)oxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide;scobro;buscol;joscine;donopon;scobron;Stibron
- CBNumber:
- CB00131464
- Molecular Formula:
- C21H30BrNO4
- Molecular Weight:
- 440.37
- MDL Number:
- MFCD00078561
- MOL File:
- 149-64-4.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 142-1440C |
|---|---|
| alpha | D20 -20.8° (c = 3 in water) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | white |
| optical activity | [α]25/D 20.8°, c = 3 in H2O(lit.) |
| CAS DataBase Reference | 149-64-4(CAS DataBase Reference) |
| FDA UNII | 0GH9JX37C8 |
| NCI Drug Dictionary | butylscopolamine bromide |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H332 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YM3500000 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 15.6 i.v.; 74 i.p.; 570 s.c.; 3000 orally (Stockhaus, Wick) | |||||||||
| NFPA 704 |
|
Hyoscine Butylbromide price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S7882 | (?)-Scopolamine N-butyl bromide ≥98% (TLC), powder | 149-64-4 | 1g | $54.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | S7882 | (?)-Scopolamine N-butyl bromide ≥98% (TLC), powder | 149-64-4 | 5g | $171 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP198 | Hyoscine butylbromide British Pharmacopoeia (BP) Reference Standard | 149-64-4 | 100MG | $229 | 2024-03-01 | Buy |
| Cayman Chemical | 27223 | Scopolamine N-butyl (bromide) | 149-64-4 | 1g | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 27223 | Scopolamine N-butyl (bromide) | 149-64-4 | 10g | $299 | 2024-03-01 | Buy |
Hyoscine Butylbromide Chemical Properties,Uses,Production
Description
Hyoscine butylbromide (scopolamine butylbromide) [Buscopan/Buscapina] is an antispasmodic drug indicated for the treatment of abdominal pain associated with cramps induced by gastrointestinal (GI) spasms. It was first registered in Germany in 1951 and marketed in 1952, and has since become available worldwide both as a prescription drug and as an over-the-counter medicine in many countries.
Uses
Hyoscine butylbromide is an antispasmodic medicine which is taken to relieve cramps in the stomach, intestines or bladder. In particular, it helps to ease bloating and the spasm-type pain that can be associated with irritable bowel syndrome and diverticular disease. It works by relaxing some of the muscles in your gastrointestinal and urinary systems.
Pharmacokinetics
Pharmacological studies have revealed that hyoscine butylbromide is an anticholinergic drug with high affinity for muscarinic receptors located on the smooth-muscle cells of the GI tract. Its anticholinergic action exerts a smooth-muscle relaxing/spasmolytic effect. Blockade of the muscarinic receptors in the GI tract is the basis for its use in the treatment of abdominal pain secondary to cramping.
Synthesis of Hyoscine Butylbromide from Methyl bromide and Benzeneacetic acid, α-(hydroxymethyl)-, 9-butyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, [7(S)-(1α,2β,4β,5α,7β)]- (9CI)
Hyoscine Butylbromide Preparation Products And Raw materials
Global( 443)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12830 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5855 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21632 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
View Lastest Price from Hyoscine Butylbromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-25 | Scopolamine butylbromide
149-64-4
|
US $0.00 / kg | 1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2019-12-23 | HYOSCINE HYDROCHLORIDE
55-16-3
|
US $1.00 / KG | 1KG | 98% HPLC | 10t | Career Henan Chemical Co | |
 |
2019-07-10 | Scopolamine butylbromide
149-64-4
|
US $1.00 / KG | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- Scopolamine butylbromide
149-64-4
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- HYOSCINE HYDROCHLORIDE
55-16-3
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co
-
- Scopolamine butylbromide
149-64-4
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
149-64-4(Hyoscine Butylbromide)Related Search:
1of4
donopon
hyoscinebutobromide
hyoscin-n-butylbromid
hyoscin-n-butylbromide
joscine
monospan
n-butylhyoscinebromide
n-butylhyosciniumbromide
n-butylscopolaminiumbromide
omide,(-)-tropate
scobro
scobron
scobutil
scobutyl
scopolaminebromobutylate
scopolaminebutobromide
scopolaminebutylbromide
scopolan
sparicon
sporamin
stilbron
tirantil
hyoscine butylobromide
Hyoscine butyl bromide BP
HYOSCINE BUTYLBROMIDE STANDARD
ScopolaMine ButylborMide (Hyoscine ButylbroMide)
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-Methyl-, broMide (1:1), (1a,2b,4b,5a,7b)-
Hyoscine butylbromide Impurity
Ding bromate scopolamine
Hyoscinen buty1bromide
Ding bromine scopolamine
()-N-Butylscopolamine bromide ()-Scopolamine N-butyl bromide Hyoscine N-butyl bromide
(-)-SCOPOLAMINE N-BUTYL BROMIDE CHOLINERGIC ANTAGONIST
3-Oxa-9-azoniatricyclo3.3.1.02,4nonane, 9-butyl-7-(2S)-3-hydroxy-1-oxo-2-phenylpropoxy-9-methyl-, bromide, (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-
1aH,5aH-Tropanium, 8-butyl-6b,7b-epoxy-3a-hydroxy-, bromide, (-)-tropate (8CI)
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, [7(S)-(1a,2b,4b,5a,7b)]-
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1a,2b,4b,5a,7b)- (9CI)
Sporamin (pharmaceutical)
Stibron
Tropic acid, (-)-, ester with 8-butyl-6b,7b-epoxy-3a-hydroxy-1a-H,5aH-tropanium bromide (8CI)
(-)-Scopolamin-n-butylbromid
(-)-SCOPOLAMINE N-BUTYL BROMIDE 99%
ButylscopolaMine BR (ScopolaMine butylbroMide)
(-)-SCOPOLAMINE N-BUTYL BROMIDE BP
7(S)-(1a,2,4,5a,7)]-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
(-)-N-Butylscopolamine bromide, Hyoscine N-butyl bromide
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1a,2b,4b,5a,7b)-
(7(S)-(1alpha,2beta,4beta,5alpha,7beta))-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azonitricyclo[3.3.1.0(2,4)]nonane bromide
Scopoamine Butylbromide
ButylscopolaMine broMide(ScopolaMine butylbroMide)
7(S)-(1α,2β,4β,5α,7β)]-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-Methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane BroMide
Buthylhyoscine bromide
BUTYLMIN
SCOPOLAMINI BUTYLBROMIDUM
(-)-SCOPOLAMINE N-BUTYL BROMIDE
SCOPOLAMINE N-BUTYL BROMIDE
(-)-N-BUTYLSCOPOLAMIDE BROMIDE
N-BUTYLSCOPOLAMMONIUM BROMIDE