ChemicalBook >> CAS DataBase List >>3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
![3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Structure](CAS/GIF/34576-94-8.gif)
- CAS No.
- 34576-94-8
- Chemical Name:
- 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
- Synonyms
- BT2;3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXY;3,6-dichlorobenzothiophene-2-carboxylic acid;3,6-dichloro-2-benzothiophenecarboxylic acid;Bcl-2 Family,BT2,Inhibitor,BT-2,inhibit,BT 2;3,6-Dichloro-1-benzothiophene-2-carboxylicaci;3,6-Dichlorobenzo[β]thiophene-2-carboxylic acid;Benzo[b]thiophene-2-carboxylic acid, 3,6-dichloro-;JR-6478, 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid, 97%
- CBNumber:
- CB01492789
- Molecular Formula:
- C9H4Cl2O2S
- Molecular Weight:
- 247.1
- MDL Number:
- MFCD00781745
- MOL File:
- 34576-94-8.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:13
| Boiling point | 426.4±40.0 °C(Predicted) |
|---|---|
| Density | 1.653±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (up to at least 20 mg/ml) |
| form | solid |
| pka | 2.09±0.30(Predicted) |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H302-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22948 | 3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid ≥95% | 34576-94-8 | 100mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22948 | 3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid ≥95% | 34576-94-8 | 250mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 22948 | 3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid ≥95% | 34576-94-8 | 500mg | $109 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | COR0002384 | 3,6-DICHLOROBENZO[B]THIOPHENE-2-CARBOXYLIC ACID 95.00% | 34576-94-8 | 1G | $721.57 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD57151 | 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid | 34576-94-8 | 2g | $450 | 2021-12-16 | Buy |
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production
Description
3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. It has been used as a building block in the synthesis of inhibitors of Mcl-1, the toll-like receptor 3/double-stranded RNA (TLR3/dsRNA) complex, and D-amino acid oxidase (DAO).
References
1) Tso et al. (2014), Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase; J. Biol. Chem., 289 20583 2) Friberg et al. (2013), Discovery of potent myeloid cell leukemia (Mcl 1) inhibitors using fragment based methods and structure based design; J. Med. Chem. 56 15
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 77)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29896 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1301 | 58 |
| Suzhou Laing Biotechnology Co.,Ltd | +86-13004516015 +86-18149392822 | christina@laingbiotec.com | China | 778 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 | cherry@crovellbio.com | China | 18433 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5986 | 58 |
View Lastest Price from 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID pictures](/ProductImageEN/2022-07/Small/54a795a4-8607-4270-b8b9-cbd39b083cf6.jpg) |
2023-09-24 | 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
34576-94-8
|
US $0.00-0.00 / g | 50g | 98% | 500kg | Suzhou Laing Biotechnology Co.,Ltd | |
![3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/cbdd3ada-bc7a-4401-9c6e-84c6ccc855f0.png) |
2019-07-06 | 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
34576-94-8
|
US $1.00 / KG | 1KG | 96% | 500kg | Career Henan Chemical Co |
-
- 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
34576-94-8
- US $0.00-0.00 / g
- 98%
- Suzhou Laing Biotechnology Co.,Ltd
-
- 3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
34576-94-8
- US $1.00 / KG
- 96%
- Career Henan Chemical Co
34576-94-8(3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID)Related Search:
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3,6-dichloro-2-benzothiophenecarboxylic acid
3,6-dichlorobenzothiophene-2-carboxylic acid
BT2
JR-6478, 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid, 97%
Benzo[b]thiophene-2-carboxylic acid, 3,6-dichloro-
3,6-Dichloro-1-benzothiophene-2-carboxylicaci
3,6-DICHLORO-BENZO[B]THIOPHENE-2-CARBOXY
Bcl-2 Family,BT2,Inhibitor,BT-2,inhibit,BT 2
3,6-Dichlorobenzo[β]thiophene-2-carboxylic acid
34576-94-8