2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
- CAS No.
- 60762-57-4
- Chemical Name:
- 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
- Synonyms
- Pirlindol;Pyrazidol;Pirlindole;Pirlindolum;Unii-V39yph45fz;PIRLINDOLE MESYLATE;Pirlindole free base;Ombitasvir Impurity 6;Pirlindolum [inn-latin];16154-78-2 (Hydrochloride)
- CBNumber:
- CB0671512
- Molecular Formula:
- C15H18N2
- Molecular Weight:
- 226.32
- MDL Number:
- MFCD00407230
- MOL File:
- 60762-57-4.mol
storage temp. | Store at RT |
---|---|
solubility | DMF: 1 mg/ml; DMSO: 5 mg/ml |
form | A crystalline solid |
color | Off-white to light yellow |
FDA UNII | V39YPH45FZ |
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 22060 | Pirlindole ≥98% | 60762-57-4 | 5mg | $71 | 2024-03-01 | Buy |
Cayman Chemical | 22060 | Pirlindole ≥98% | 60762-57-4 | 10mg | $133 | 2024-03-01 | Buy |
Cayman Chemical | 22060 | Pirlindole ≥98% | 60762-57-4 | 25mg | $313 | 2024-03-01 | Buy |
Cayman Chemical | 22060 | Pirlindole ≥98% | 60762-57-4 | 50mg | $590 | 2024-03-01 | Buy |
Tocris | 0724 | Pirlindolemesylate | 60762-57-4 | 50 | $628 | 2021-12-16 | Buy |
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Chemical Properties,Uses,Production
Description
Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 μM independent of MAO-A activity.
Uses
Antidepressive;Monoamine oxidase inhibitor
Biological Activity
A highly selective reversible inhibitor of monoamine oxidase type A.
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8072 | 58 |
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb6@aikonchem.com | China | 16687 | 50 |
Tcichem, Inc. | 13918644899 | tianchong009@hotmail.com | China | 1764 | 55 |
60762-57-4(2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE)Related Search:
1of2