Nodinitib-1
- CAS No.
- 799264-47-4
- Chemical Name:
- Nodinitib-1
- Synonyms
- ML 130;Nodinitib-1;Noditinib-1;CID-1088438;Noditiniβ-1;ML-130;ML 130;130 (Nodinitib-1);ML130;CID-1088438;ML130 (Nodinitib-1);Nodinitib-1 USP/EP/BP
- CBNumber:
- CB12591864
- Molecular Formula:
- C14H13N3O2S
- Molecular Weight:
- 287.34
- MDL Number:
- MFCD04322367
- MOL File:
- 799264-47-4.mol
- MSDS File:
- SDS
| Melting point | 191-192 °C (decomp) |
|---|---|
| Boiling point | 532.5±43.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO: >10mg/mL |
| pka | 2.55±0.10(Predicted) |
| form | powder |
| color | white to beige |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Nodinitib-1 price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0379 | Nodinitib-1 ≥98% (HPLC) | 799264-47-4 | 5mg | $79.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0379 | Nodinitib-1 ≥98% (HPLC) | 799264-47-4 | 25mg | $523 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 25mg | $193 | 2024-03-01 | Buy |
Nodinitib-1 Chemical Properties,Uses,Production
Uses
Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.
Definition
ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.
Biological Activity
Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
IC 50
NOD1
Nodinitib-1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22854 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from Nodinitib-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Nodinitib-1
799264-47-4
|
US $50.00-143.00 / mg | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-12-24 | Nodinitib-1
799264-47-4
|
US $1.00 / g | 1g | 99% | 20kg | Career Henan Chemical Co |
-
- Nodinitib-1
799264-47-4
- US $50.00-143.00 / mg
- 99.98%
- TargetMol Chemicals Inc.
-
- Nodinitib-1
799264-47-4
- US $1.00 / g
- 99%
- Career Henan Chemical Co