Nodinitib-1
|
- $44 - $2400
- Product name: Nodinitib-1
- CAS: 799264-47-4
- MF: C14H13N3O2S
- MW: 287.34
- EINECS:
- MDL Number:MFCD04322367
- Synonyms:Nodinitib-1;1H-BenziMidazol-2-aMine, 1-[(4-Methylphenyl)sulfonyl]-;ML 130;1-[(4-Methylphenyl)sulfonyl]-1H-benziMidazol-2-aMine;Noditinib-1;ML130 (Nodinitib-1);CID-1088438;1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-ylamine
36 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10mg
- 10
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- ManufacturerAK Scientific
- Product number2553AH
- Product description1-[(4-Methylbenzene)sulfonyl]-1H-1,3-benzodiazol-2-amine
- Packaging50mg
- Price$344
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104782
- Product descriptionML130 95+%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104782
- Product descriptionML130 95+%
- Packaging10mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104782
- Product descriptionML130 95+%
- Packaging25mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104782
- Product descriptionML130 95+%
- Packaging100mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001503
- Product descriptionML-130 99.00%
- Packaging5MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001503
- Product descriptionML-130 99.00%
- Packaging10MG
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001503
- Product descriptionML-130 99.00%
- Packaging50MG
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1646
- Product descriptionML130(Nodinitib-1)
- Packaging10mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1646
- Product descriptionML130(Nodinitib-1)
- Packaging25mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1646
- Product descriptionML130(Nodinitib-1)
- Packaging50mg
- Price$389
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11040
- Product descriptionNodinitib-1 ≥95%
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11040
- Product descriptionNodinitib-1 ≥95%
- Packaging10mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11040
- Product descriptionNodinitib-1 ≥95%
- Packaging25mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11040
- Product descriptionNodinitib-1 ≥95%
- Packaging50mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM255095
- Product description1-Tosyl-1H-benzo[d]imidazol-2-amine 95%
- Packaging100mg
- Price$368
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2553AH | 1-[(4-Methylbenzene)sulfonyl]-1H-1,3-benzodiazol-2-amine | 50mg | $344 | 2021-12-16 | Buy |
| Ambeed | A104782 | ML130 95+% | 5mg | $60 | 2021-12-16 | Buy |
| Ambeed | A104782 | ML130 95+% | 10mg | $84 | 2021-12-16 | Buy |
| Ambeed | A104782 | ML130 95+% | 25mg | $142 | 2021-12-16 | Buy |
| Ambeed | A104782 | ML130 95+% | 100mg | $313 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001503 | ML-130 99.00% | 5MG | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001503 | ML-130 99.00% | 10MG | $470 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001503 | ML-130 99.00% | 50MG | $630 | 2021-12-16 | Buy |
| ApexBio Technology | B1646 | ML130(Nodinitib-1) | 10mg | $92 | 2021-12-16 | Buy |
| ApexBio Technology | B1646 | ML130(Nodinitib-1) | 25mg | $219 | 2021-12-16 | Buy |
| ApexBio Technology | B1646 | ML130(Nodinitib-1) | 50mg | $389 | 2021-12-16 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 25mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 50mg | $341 | 2024-03-01 | Buy |
| Chemenu | CM255095 | 1-Tosyl-1H-benzo[d]imidazol-2-amine 95% | 100mg | $368 | 2021-12-16 | Buy |
Properties
Melting point :191-192 °C (decomp)
Boiling point :532.5±43.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :2.55±0.10(Predicted)
color :white to beige
Boiling point :532.5±43.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :2.55±0.10(Predicted)
color :white to beige
Safety Information
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Description
NOD1 is a member of the NACHT and leucine-rich repeat domain-containing proteins (NLR) family of innate immunity proteins. It recognizes distinct molecular patterns from bacterial ligands and activates NF-κB, stress kinases, and interferon response factors important for host defense and inflammation. Hereditary polymorphisms in the NOD1 gene are associated with asthma, inflammatory bowel disease, multiple sclerosis, and other disorders. Noditinib-1 selectively inhibits NOD1-dependent activation of NF-κB and MAPK signaling (IC50 = 0.6 μM) and also inhibits NOD1-induced IL-8 production in MCF-7 cells without affecting viability. In ex vivo dendritic cell culture, 15 μM noditinib-1 reduced cell-surface expression of CD83, CD86, and HLA-DR and inhibited expression of IL-1β, IL-6, and TNF-α. The mechanism of this inhibitor’s activity is thought to involve alteration of the subcellular targeting of NOD1.More related product prices
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