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ChemicalBook >> CAS DataBase List >>2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Structure
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide structure
CAS No.
1486482-16-9
Chemical Name:
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
Synonyms
ML251;2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide;2-(3,4-Dichlorophenyl)-N-(4-(N-(isoxazol-3-yl)sulfamoyl)phenyl)acetamide;cruzi,inhibit,brucei,MRC-5,Inhibitor,nanomolar,Parasite,ML-251,ML 251,ML251
CBNumber:
CB43839951
Molecular Formula:
C17H13Cl2N3O4S
Molecular Weight:
426.27382
MDL Number:
MFCD28411402
MOL File:
1486482-16-9.mol
Last updated:2024-11-19 23:02:33
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2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Properties

storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (586.48 mM; Need ultrasonic)
form Solid
color White to off-white

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Chemical Properties,Uses,Production

Biological Activity

ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1].

References

[1]. Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17.

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4566 55
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465 sales@zehanbiopharma.com China 1005 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 4597 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8012 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2991 58
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 7290 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
Aladdin Scientific 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghaizehan biopharma technology co., Ltd. 55
Tianjin Kailiqi Biotechnology Co., Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
Shanghai Rechem science Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58

View Lastest Price from 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ML251 pictures 2024-11-19 ML251
1486482-16-9
 US $135.00-455.00 / mg 99.87% 10g TargetMol Chemicals Inc.
  • ML251 pictures
  • ML251
    1486482-16-9
  • US $135.00-455.00 / mg
  • 99.87%
  • TargetMol Chemicals Inc.

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2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide ML251 2-(3,4-Dichlorophenyl)-N-(4-(N-(isoxazol-3-yl)sulfamoyl)phenyl)acetamide cruzi,inhibit,brucei,MRC-5,Inhibitor,nanomolar,Parasite,ML-251,ML 251,ML251 1486482-16-9