ARP100
- CAS No.
- 704888-90-4
- Chemical Name:
- ARP100
- Synonyms
- ARP100;MMP-2 Inhibitor III;ARP-100, 10 mM in DMSO;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
- CBNumber:
- CB21075595
- Molecular Formula:
- C17H20N2O5S
- Molecular Weight:
- 364.42
- MDL Number:
- MFCD09971105
- MOL File:
- 704888-90-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
ARP100 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 444288 | MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem | 704888-90-4 | 5mg | $332 | 2024-03-01 | Buy |
| Alfa Aesar | J64151 | ARP 100 | 704888-90-4 | 5mg | $83.9 | 2021-12-16 | Buy |
| Cayman Chemical | 13321 | ARP 100 ≥98% | 704888-90-4 | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 13321 | ARP 100 ≥98% | 704888-90-4 | 5mg | $104 | 2024-03-01 | Buy |
| Cayman Chemical | 13321 | ARP 100 ≥98% | 704888-90-4 | 10mg | $186 | 2024-03-01 | Buy |
ARP100 Chemical Properties,Uses,Production
Uses
ARP 100 is a potent, dual inhibitor of MMP-12/MMP-13 targets, which are a family of zinc dependent endopeptidases known to play key roles in extracellular matrix (ECM) breakdown disorders, such as the two main forms of arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA).
Uses
A selective inhibitor of MMP-2
Biological Activity
Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.
IC 50
MMP-2: 12 nM (IC50); MMP-9: 0.2 μM (IC50); MMP-3: 4.5 μM (IC50); MMP-1: >50 μM (IC50); MMP-7: >50 μM (IC50)
ARP100 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 | |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
