ACRIFLAVINE
- CAS No.
- 8048-52-0
- Chemical Name:
- ACRIFLAVINE
- Synonyms
- diacrid;flavine;gonacin;isravin;angiflan;flavipin;EUFLAVIN;CI 46000;flavisept;gonacrine
- CBNumber:
- CB2225391
- Molecular Formula:
- C27H25ClN6
- Molecular Weight:
- 468.98
- MDL Number:
- MFCD00064307
- MOL File:
- 8048-52-0.mol
- MSDS File:
- SDS
| Melting point | 179-181 °C |
|---|---|
| Boiling point | 612.69°C (rough estimate) |
| Density | 1.0933 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Store at -20°C |
| solubility | H2O: soluble0.33g/mL (lit.)(lit.) |
| form | Powder |
| color | Deep orange to brownish-red |
| Water Solubility | H2O: 0.33g/mL (lit.)(lit.) |
| Merck | 14,123 |
| CAS DataBase Reference | 8048-52-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 1T3A50395T |
| EPA Substance Registry System | Xanthacridinum (8048-52-0) |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-37/38-41-50/53-20/21/22-50-36/37/38 | |||||||||
| Safety Statements | 26-39-60-61-36-37/39-29-36/37/39 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AR9660000 | |||||||||
| HS Code | 38249064 | |||||||||
| NFPA 704 |
|
ACRIFLAVINE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A8126 | Acriflavine | 8048-52-0 | 25g | $79.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | A8126 | Acriflavine | 8048-52-0 | 100g | $275 | 2024-03-01 | Buy |
| TCI Chemical | A0134 | Acriflavine (mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine) >70.0%(HPLC) | 8048-52-0 | 25g | $51 | 2024-03-01 | Buy |
| Sigma-Aldrich | 01673 | Acriflavine BioReagent, suitable for fluorescence, ≥95.0% (AT) | 8048-52-0 | 10g | $71.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 01673 | Acriflavine BioReagent, suitable for fluorescence, ≥95.0% (AT) | 8048-52-0 | 50g | $212 | 2024-03-01 | Buy |
ACRIFLAVINE Chemical Properties,Uses,Production
Chemical Properties
Acriflavine hydrochloride is deep orange to brownish-red powder
Uses
Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.
Uses
Fluorescent label for high molecular weight RNA
Biological Activity
Acriflavine also interacts with HIF-1α (hypoxia-inducible factor 1 α) and HIF-2α, and thereby suppresses dimer formation of HIF-1 and transcriptional function. It also has negative effect on tumor growth and vascularization. Acriflavine also exhibits trypanocidal, antibacterial and antiviral activities.
Safety Profile
Poison by subcutaneous route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. A topical antiseptic used in the treatment of gonorrhea. When heated to decomposition it emits very toxic fumes of NOx and Cl-. See also 3,6-DIAMINO-10 METHYLACRIDINIUM CHLORIDE.
Purification Methods
Treat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.]
ACRIFLAVINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29859 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22854 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5971 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
View Lastest Price from ACRIFLAVINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-24 | Acriflavine
8048-52-0
|
US $0.00 / G | 100G | 98%min | 30KG/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-03-03 | ACRIFLAVINE
8048-52-0
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-11-19 | Acriflavine
8048-52-0
|
US $105.00-34.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Acriflavine
8048-52-0
- US $0.00 / G
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- ACRIFLAVINE
8048-52-0
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Acriflavine
8048-52-0
- US $105.00-34.00 / mg
- TargetMol Chemicals Inc.
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