PROGLUMIDE, SODIUM SALT
- CAS No.
- 99247-33-3
- Chemical Name:
- PROGLUMIDE, SODIUM SALT
- Synonyms
- PROGLUMIDE SODIUM;PROGLUMIDE, SODIUM SALT;Proglumide sodium salt solid;PROGLUMIDE SODIUM SALT SELECTIVE CHOLECY STOK;4-benzamido-5-(dipropylamino)-5-oxopentanoate;dl-4-benzamido-n,n-dipropylglutaramicacidsodiumsalt;SODIUM;4-BENZAMIDO-5-(DIPROPYLAMINO)-5-OXOPENTANOATE;4-benzamido-n,n-dipropyl-,sodiumsalt,dl-glutaramicaci;4-BENZOYLAMINO-5-DIPROPYLAMINO-5-OXOPENTANOIC ACID SODIUM;Glutaramic acid, 4-benzamido-N,N-dipropyl-, sodium salt, DL-
- CBNumber:
- CB3125814
- Molecular Formula:
- C18H27N2NaO4
- Molecular Weight:
- 358.41
- MDL Number:
- MFCD00069301
- MOL File:
- 99247-33-3.mol
storage temp. | Desiccate at RT |
---|---|
solubility | H2O: soluble |
form | solid |
color | white |
Water Solubility | Soluble to 100 mM in water |
EWG's Food Scores | 1 |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
PROGLUMIDE, SODIUM SALT price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M006 | Proglumide sodium salt solid | 99247-33-3 | 100mg | $179 | 2024-03-01 | Buy |
Sigma-Aldrich | M006 | Proglumide sodium salt solid | 99247-33-3 | 500mg | $1130 | 2024-03-01 | Buy |
Tocris | 1478 | Proglumide sodium salt ≥98%(HPLC) | 99247-33-3 | 50 | $64 | 2021-12-16 | Buy |
Usbiological | 256329 | Proglumide sodium salt | 99247-33-3 | 50mg | $290 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0014081 | PROGLUMIDE SODIUM SALT 99.00% | 99247-33-3 | 5MG | $503.68 | 2021-12-16 | Buy |
PROGLUMIDE, SODIUM SALT Chemical Properties,Uses,Production
Uses
Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
Biochem/physiol Actions
Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.
in vivo
Proglumide (250-750 mg/kg; intraperitoneal injection; adult male Sprague Dawley rats) treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1].
Animal Model: | Adult male Sprague Dawley rats (200-250?g; 2 months old) are induced status epilepticus (SE)[1] |
Dosage: | 250 mg/kg, 500 mg/kg, and 750?mg/kg |
Administration: | Intraperitoneal injection |
Result: | Dose-dependently and significantly increased the latencies to seizure and SE. Significantly and dose-dependently attenuated Li-PC (SE) induced increase in thiobarbituric acid (TBARS) and catalase (CAT), attenuated Li-Pc induced decrease in SOD, and attenuated depletion of GSH and glutathione-S transferase (GST) in the hippocampus and striatum. |
storage
Desiccate at RT
PROGLUMIDE, SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
PROGLUMIDE, SODIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4720 | 55 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9409 | 58 |
View Lastest Price from PROGLUMIDE, SODIUM SALT manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-10-24 | Proglumide sodium
99247-33-3
|
US $198.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Proglumide sodium
99247-33-3
- US $198.00 / mg
- TargetMol Chemicals Inc.