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2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-

CAS No.
1010096-65-7
Chemical Name:
2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-
Synonyms
AM6701;LY2183240 2’LY2183240 2’-isomer;LY2183240 2'-isomer Exclusive;5-([1,1-biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide;2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-
CBNumber:
CB32667875
Molecular Formula:
C17H17N5O
Molecular Weight:
307.35
MDL Number:
MOL File:
1010096-65-7.mol
Last updated:2024-07-02 08:55:06

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Properties

Boiling point 506.1±53.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.1 mg/ml
form A crystalline solid
pka -1.73±0.12(Predicted)
color Light yellow to yellow
FDA UNII 5TVW7VFN92

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14523 LY2183240 2’-isomer ≥98% 1010096-65-7 1mg $93 2024-03-01 Buy
Cayman Chemical 14523 LY2183240 2’-isomer ≥98% 1010096-65-7 5mg $252 2024-03-01 Buy
Cayman Chemical 14523 LY2183240 2’-isomer ≥98% 1010096-65-7 10mg $451 2024-03-01 Buy
TRC T310905 5-([1,1''-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide 1010096-65-7 100mg $1055 2021-12-16 Buy
AK Scientific 1493DC 5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide 1010096-65-7 1mg $201 2021-12-16 Buy
Product number Packaging Price Buy
14523 1mg $93 Buy
14523 5mg $252 Buy
14523 10mg $451 Buy
T310905 100mg $1055 Buy
1493DC 1mg $201 Buy

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Chemical Properties,Uses,Production

Description

LY2183240 is a potent, competitive small molecule inhibitor of anandamide uptake (IC50 = 270 pM; Ki = 540 pM) and hydrolysis. It has been shown to increase anandamide levels in rat cerebellum (ED50 = 1.37 mg/kg) and displays dose-dependent efficacy (3-30 mg/kg) in several rodent models of persistent pain. LY2183240 2’-isomer is a less potent, 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and uptake with IC50 values of 33 and 998 nM, respectively.

Uses

5-([1,1''-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide is an inhibitor of human monoacylglycerol lipase (hMGL).

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
BOC Sciences -- info@bocsci.com USA 0 65
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50471 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29978 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28068 58
2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- LY2183240 2’-isomer LY2183240 2'-isomer Exclusive 5-([1,1-biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide LY2183240 2&rsquo AM6701 1010096-65-7