2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-

1010096-65-7

CAS-Nr.: 1010096-65-7

Englisch Name:: 2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-

Synonyma:: AM6701;LY2183240 2’LY2183240 2’-isomer;LY2183240 2'-isomer Exclusive;5-([1,1-biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide;2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-

CBNumber:: CB32667875

Summenformel:: C17H17N5O

Molgewicht:: 307.35

MOL-Datei:: 1010096-65-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 11

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Eigenschaften

Siedepunkt:: 506.1±53.0 °C(Predicted)

Dichte: 1.21±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.1 mg/ml

Aggregatzustand: A crystalline solid

pka: -1.73±0.12(Predicted)

Farbe: Light yellow to yellow

Sicherheit

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

LY2183240 is a potent, competitive small molecule inhibitor of anandamide uptake (IC₅₀ = 270 pM; K_i = 540 pM) and hydrolysis. It has been shown to increase anandamide levels in rat cerebellum (ED₅₀ = 1.37 mg/kg) and displays dose-dependent efficacy (3-30 mg/kg) in several rodent models of persistent pain. LY2183240 2’-isomer is a less potent, 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and uptake with IC₅₀ values of 33 and 998 nM, respectively.

Verwenden

5-([1,1''-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide is an inhibitor of human monoacylglycerol lipase (hMGL).

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 11)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 17801761073	Gsiyu@solarbio.com	China	50471	58
https://hanhongsci.com/	021-54306202 18917919676	info@hanhongsci.com	China	29990	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

2H-Tetrazole-2-carboxaMide, 5-([1,1'-biphenyl]-4-ylMethyl)-N,N-diMethyl-
LY2183240 2’-isomer
LY2183240 2'-isomer Exclusive
5-([1,1-biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide
LY2183240 2&rsquo
AM6701
1010096-65-7