SUFENTANIL CITRATE
- CAS No.
- 60561-17-3
- Chemical Name:
- SUFENTANIL CITRATE
- Synonyms
- r33800;Sufenta;Sufentanil Forte;r30730citratesalt;sufentanylcitrate;Sufentanyl Citrat;SUFENTANIL CITRATE;SUFENTANILCITRATE,USP;Sufentanil citrate salt;Rezvilutamide Impurity 38
- CBNumber:
- CB4339496
- Molecular Formula:
- C28H38N2O9S
- Molecular Weight:
- 578.68
- MDL Number:
- MFCD00072116
- MOL File:
- 60561-17-3.mol
| Melting point | 96.60C |
|---|---|
| Flash point | 9℃ |
| storage temp. | -20°C Freezer |
| solubility | H2O: soluble1mg/mL, clear |
| form | powder |
| color | white to beige |
| Stability | Hygroscopic |
| FDA UNII | S9ZFX8403R |
| NCI Drug Dictionary | Sufenta |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H310+H330 | |||||||||
| Precautionary statements | P260-P262-P264-P280-P302+P352+P310-P304+P340+P310 | |||||||||
| Hazard Codes | T+,T,F | |||||||||
| Risk Statements | 26/27/28-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 26-27-28-36/37/39-45-36/37-16-7 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2934910000 | |||||||||
| Toxicity | LD50 intravenous in dog: 14100ug/kg | |||||||||
| NFPA 704 |
|
SUFENTANIL CITRATE Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)
Definition
ChEBI: Sufentanil citrate is an anilide.
brand name
Sufenta (Akorn).
General Description
Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.
Clinical Use
Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.
Veterinary Drugs and Treatments
An opioid analgesic, sufentanil may be useful as an anesthesia adjunct or as an epidural analgesic. In humans, it has been used as the primary anesthetic in intubated patients with assisted ventilation, and as a post-operative analgesic.
SUFENTANIL CITRATE Preparation Products And Raw materials
Raw materials
Preparation Products
60561-17-3(SUFENTANIL CITRATE)Related Search:
1of4