ChemicalBook >> CAS DataBase List >>N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

CAS No.
312917-14-9
Chemical Name:
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
Synonyms
CS-320;JNK-5A;SC-20267;SC-202671;TCS JNK 5a;F0016-0404;SC-202671, >98%;JNK Inhibitor IX;TCS JNK 5a, >98%;SC-202671 TCSJNK5a
CBNumber:
CB52518872
Molecular Formula:
C20H16N2OS
Molecular Weight:
332.42
MDL Number:
MFCD01005305
MOL File:
312917-14-9.mol
Last updated:2024-11-19 23:02:33

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Properties

Melting point 88-90oC
Boiling point 486.8±45.0 °C(Predicted)
Density 1.32±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
form Tan solid
pka 11.95±0.20(Predicted)
color Off-white
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
HS Code  2934999090
NFPA 704
0
2 0

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 420136 JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem 312917-14-9 5mg $245 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 312917-14-9 5mg $62 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 312917-14-9 10mg $109 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 312917-14-9 25mg $225 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 312917-14-9 50mg $419 2024-03-01 Buy
Product number Packaging Price Buy
420136 5mg $245 Buy
15624 5mg $62 Buy
15624 10mg $109 Buy
15624 25mg $225 Buy
15624 50mg $419 Buy

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Chemical Properties,Uses,Production

Description

JNK inhibitor IX (312917-14-9) inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38α and a panel of 30 other kinases.1?Induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.2

Uses

JNK Inhibitor IX is a potent and selective inhibitor of JNK2 and JNK3. Neuroresearch & Neuroprotective Product.

Definition

ChEBI: N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide is a naphthalenecarboxamide.

storage

Store at RT

References

1) Angell?et al. (2007),?N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3; Med. Chem. Lett.,?17?1296 2) Jang?et al.?(2014),?Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells?; Biochem. Biophys. Res. Commun.,?452?845

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22784 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24727 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TCS JNK 5a pictures 2024-11-19 TCS JNK 5a
312917-14-9
US $39.00-115.00 / mg 99.5% 10g TargetMol Chemicals Inc.
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide pictures 2019-09-06 N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
312917-14-9
US $1.00 / KG 1KG 95%~99% per week 100kg Career Henan Chemical Co
  • TCS JNK 5a pictures
  • TCS JNK 5a
    312917-14-9
  • US $39.00-115.00 / mg
  • 99.5%
  • TargetMol Chemicals Inc.

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Spectrum

312917-14-9(N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide)Related Search:

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide TCS JNK 5a 1-NaphthalenecarboxaMide, N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)- SC-202671 N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide JNK Inhibitor IX N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)naphthalene-1-carboxamide JNK Inhibitor IX, >=98% TCS JNK 5a(JNK Inhibitor IX) SC-20267 JNK Inhibitor IX F0016-0404 SC-202671, >98% TCS JNK 5a, >98% JNK INHIBITOR IX;TCSJNK-5A) CS-320 JNK-5A N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide USP/EP/BP SC202671|||SC 202671|||N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide|||JNK Inhibitor IX|||SC-202671 SC-202671 TCSJNK5a 312917-14-9 Inhibitors