ChemicalBook >> CAS DataBase List >>N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide structure

CAS No.: 312917-14-9

Chemical Name:: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

Synonyms: CS-320;JNK-5A;SC-20267;SC-202671;TCS JNK 5a;F0016-0404;SC-202671, >98%;JNK Inhibitor IX;TCS JNK 5a, >98%;SC-202671 TCSJNK5a

CBNumber:: CB52518872

Molecular Formula:: C20H16N2OS

Molecular Weight:: 332.42

MDL Number:: MFCD01005305

MOL File:: 312917-14-9.mol

Last updated:2024-11-19 23:02:33

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N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Properties

Melting point	88-90oC
Boiling point	486.8±45.0 °C(Predicted)
Density	1.32±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
form	Tan solid
pka	11.95±0.20(Predicted)
color	Off-white
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

HS Code

2934999090

NFPA 704

	0
2		0

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	420136	JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem	312917-14-9	5mg	$245	2024-03-01	Buy
Cayman Chemical	15624	JNK Inhibitor IX ≥98%	312917-14-9	5mg	$62	2024-03-01	Buy
Cayman Chemical	15624	JNK Inhibitor IX ≥98%	312917-14-9	10mg	$109	2024-03-01	Buy
Cayman Chemical	15624	JNK Inhibitor IX ≥98%	312917-14-9	25mg	$225	2024-03-01	Buy
Cayman Chemical	15624	JNK Inhibitor IX ≥98%	312917-14-9	50mg	$419	2024-03-01	Buy

Product number	Packaging	Price	Buy
420136	5mg	$245	Buy
15624	5mg	$62	Buy
15624	10mg	$109	Buy
15624	25mg	$225	Buy
15624	50mg	$419	Buy

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Chemical Properties,Uses,Production

Description

JNK inhibitor IX (312917-14-9) inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38α and a panel of 30 other kinases.1?Induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.2

Uses

JNK Inhibitor IX is a potent and selective inhibitor of JNK2 and JNK3. Neuroresearch & Neuroprotective Product.

Definition

ChEBI: N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide is a naphthalenecarboxamide.

storage

Store at RT

References

1) Angell?et al. (2007),?N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3; Med. Chem. Lett.,?17?1296 2) Jang?et al.?(2014),?Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells?; Biochem. Biophys. Res. Commun.,?452?845

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Suppliers

Global( 111)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29884	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22883	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Coresyn Pharmatech Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58

View Lastest Price from N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	TCS JNK 5a 312917-14-9	US $39.00-115.00 / mg		99.5%	10g	TargetMol Chemicals Inc.
	2019-09-06	N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide 312917-14-9	US $1.00 / KG	1KG	95%~99%	per week 100kg	Career Henan Chemical Co

TCS JNK 5a
312917-14-9
US $39.00-115.00 / mg
99.5%
TargetMol Chemicals Inc.

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
312917-14-9
US $1.00 / KG
95%~99%
Career Henan Chemical Co

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide Spectrum

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide(312917-14-9)¹HNMR

312917-14-9(N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide)Related Search:

ZM 447439 ZM 306416 hydrochloride SU 4312 JX401 AS601245

JNK-IN-8 U0126-EtOH 1,9-Pyrazoloanthrone ABT-199 ABT 737

SCH772984

1of3

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide TCS JNK 5a 1-NaphthalenecarboxaMide, N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)- SC-202671 N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide JNK Inhibitor IX N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)naphthalene-1-carboxamide JNK Inhibitor IX, >=98% TCS JNK 5a(JNK Inhibitor IX) SC-20267 JNK Inhibitor IX F0016-0404 SC-202671, >98% TCS JNK 5a, >98% JNK INHIBITOR IX;TCSJNK-5A) CS-320 JNK-5A N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide USP/EP/BP SC202671|||SC 202671|||N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide|||JNK Inhibitor IX|||SC-202671 SC-202671 TCSJNK5a 312917-14-9 Inhibitors