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HA-100 (hydrochloride)

CAS No.
210297-47-5
Chemical Name:
HA-100 (hydrochloride)
Synonyms
HA-100 dihydrochloride DISCONTINUED, Offer I891000;5-piperazin-1-ylsulfonylisoquinoline:dihydrochloride
CBNumber:
CB53152624
Molecular Formula:
C13H16ClN3O2S
Molecular Weight:
313.8
MDL Number:
MFCD01310980
MOL File:
210297-47-5.mol
Last updated:2023-06-08 09:03:09

HA-100 (hydrochloride) Properties

storage temp. Store at -20°C
solubility insoluble in EtOH; ≥131.8 mg/mL in H2O; ≥19.17 mg/mL in DMSO with ultrasonic
form A crystalline solid

SAFETY

Risk and Safety Statements

HA-100 (hydrochloride) price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14955 HA-100 (hydrochloride) ≥95% 210297-47-5 5mg $63 2024-03-01 Buy
Cayman Chemical 14955 HA-100 (hydrochloride) ≥95% 210297-47-5 10mg $119 2024-03-01 Buy
Cayman Chemical 14955 HA-100 (hydrochloride) ≥95% 210297-47-5 25mg $247 2024-03-01 Buy
Cayman Chemical 14955 HA-100 (hydrochloride) ≥95% 210297-47-5 50mg $465 2024-03-01 Buy
ApexBio Technology C4953 HA-100(hydrochloride) 210297-47-5 50mg $544 2021-12-16 Buy
Product number Packaging Price Buy
14955 5mg $63 Buy
14955 10mg $119 Buy
14955 25mg $247 Buy
14955 50mg $465 Buy
C4953 50mg $544 Buy

HA-100 (hydrochloride) Chemical Properties,Uses,Production

Description

HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 μM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 μM).

Uses

HA-100 dihydrochloride is an inhibitor of MYLK, PKA, and PKC.

References

[1] hagiwara m, inagaki m, watanabe m, et al. selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives[j]. molecular pharmacology, 1987, 32(1): 7-12.
[2] krebs e g. protein kinases[j]. current topics in cellular regulation, 1972, 5: 99-133.

HA-100 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

HA-100 (hydrochloride) Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8019 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2998 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shandong Jirun Biomedical Technology Co., Ltd. 0539-0539-8613587 17661611089 2639273505@qq.com China 164 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Wuhan Topule +86-02787215551 +86-19945035818 2936752263@qq.com China 8237 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 6637 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58

HA-100 (hydrochloride) Spectrum

5-piperazin-1-ylsulfonylisoquinoline:dihydrochloride HA-100 dihydrochloride DISCONTINUED, Offer I891000 210297-47-5 C13H15N3O2S2HCl