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Fmoc-Leu-OH

CAS No.
35661-60-0
Chemical Name:
Fmoc-Leu-OH
Synonyms
FMOC-LEU-OH;FMOC-LEU;FMOC-L-LEU-OH;FMOC-LEUCINE;L-LEUCINE-N-FMOC;N-(fluorenyl-9-methoxycarbonyl)leucine;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid;F-L-LEU;NPC 15199;FMOC-L-LEU
CBNumber:
CB5477829
Molecular Formula:
C21H23NO4
Molecular Weight:
353.41
MDL Number:
MFCD00037133
MOL File:
35661-60-0.mol
MSDS File:
SDS
Last updated:2024-11-14 14:09:35

Fmoc-Leu-OH Properties

Melting point 152-156 °C(lit.)
alpha -26 º (c=1,DMF 24 ºC)
Boiling point 486.83°C (rough estimate)
Density 1.2107 (rough estimate)
refractive index -25 ° (C=1, DMF)
storage temp. Store below +30°C.
solubility DMF (Slightly), DMSO (Slightly)
pka 3.91±0.21(Predicted)
form Solid
color White to Off-White
optical activity [α]20/D 25±2°, c = 1% in DMF
BRN 2178254
Stability Hygroscopic
InChIKey CBPJQFCAFFNICX-IBGZPJMESA-N
CAS DataBase Reference 35661-60-0(CAS DataBase Reference)
FDA UNII KF18F70UF3

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-27-26
WGK Germany  3
HS Code  2924 29 70
NFPA 704
1
1 0

Fmoc-Leu-OH price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52011 Fmoc-Leu-OH Novabiochem? 35661-60-0 25g $36.5 2024-03-01 Buy
Sigma-Aldrich 8.52011 Fmoc-Leu-OH Novabiochem? 35661-60-0 100g $70 2024-03-01 Buy
Sigma-Aldrich 8.52011 Fmoc-Leu-OH Novabiochem? 35661-60-0 250g $162 2024-03-01 Buy
Sigma-Aldrich 8.52011 Fmoc-Leu-OH Novabiochem? 35661-60-0 1kg $489 2024-03-01 Buy
Sigma-Aldrich 47633 Fmoc-Leu-OH ≥97.0% 35661-60-0 5G $32.3 2024-03-01 Buy
Product number Packaging Price Buy
8.52011 25g $36.5 Buy
8.52011 100g $70 Buy
8.52011 250g $162 Buy
8.52011 1kg $489 Buy
47633 5G $32.3 Buy

Fmoc-Leu-OH Chemical Properties,Uses,Production

Description

Fmoc-Leu-OH is isomeric with Fmoc-Ile-OH. Like isoleucine, leucine has branching in the sidechain. The branching is at the gamma carbon instead of the beta carbon as in isoleucine. It is used in chemical and peptide syntheses.

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.

Application

Fmoc-Leu-OH can be used as a reactant to synthesize:
Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.
A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.
Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.
Coumaroyl dipeptide amide that can be used for cosmetic applications.

Preparation

Fmoc-L-leucine is prepared by reacting L-leucine with 9-fluorenylmethoxycarbonyl chloride.

Biological Activity

Anti-inflammatory agent; increases intracellular Ca 2+ levels. PPARγ ligand that induces insulin sensitization, but not adipogenesis.

Fmoc-Leu-OH Preparation Products And Raw materials

Global( 625)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Baishixing Science and Technology Industry Co.,Ltd
+86-15008457246 +86-15008457246 yuki@cd-bsx.com China 53 58
Lanxi Xingnuo Import and Export Trading Co., Ltd
+86-15888978871 +86-13901546477 sales@xingnuotraders.com China 163 58
Chengdu ZY Biochemical Technology Co., Ltd.
+86-86-2888626688 +8618980008884 xuehaiying@zybiochem.com China 125 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097 market02@senwayer.com China 904 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8617390183901 daisy@enlaibio.com China 1106 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18751 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58

View Lastest Price from Fmoc-Leu-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-L-leu-OH pictures 2024-12-23 Fmoc-L-leu-OH
35661-60-0
US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
FMOC-L-Leucine pictures 2024-12-13 FMOC-L-Leucine
35661-60-0
US $0.00 / Kg/Drum 1KG 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
NPC 15199 pictures 2024-11-14 NPC 15199
35661-60-0
US $29.00 / mg 99.94% 10g TargetMol Chemicals Inc.
  • Fmoc-L-leu-OH pictures
  • Fmoc-L-leu-OH
    35661-60-0
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • FMOC-L-Leucine pictures
  • FMOC-L-Leucine
    35661-60-0
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • NPC 15199 pictures
  • NPC 15199
    35661-60-0
  • US $29.00 / mg
  • 99.94%
  • TargetMol Chemicals Inc.
FMOC-L-LEU FMOC-L-LEUCINE F-L-LEU Fmoc-L-leucine,98% L-Leucine-1-13C-N-FMOC Fmoc-N-(isobutyl)-glycine FMOC-L-LEU-OH MONOHYDRATE Fmoc-N-(isobutyl)-Gly-OH FMOC-L-LEUCINE extrapure N-(9-Fluorenylmethoxycarbonyl)-L-leucine, Fmoc-L-leucine 2-(9H-fFuoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine ,98% (2S)-4-Methyl-2-(9H-fluorene-9-ylmethoxycarbonylamino)valeric acid (S)-2-[[(9H-Fluorene-9-yl)methoxycarbonyl]amino]-4-methylpentanoic acid N-[(9H-Fluorene-9-yl)methoxycarbonyl]leucine FMoc-L-leucine FMoc-Leu-OH 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-4-METHYLPENTANOIC ACID 9-FLUORENYLMETHOXYCARBONYL-L-LEUCINE Fmoc-Leucine-OH FMoc-Nleu-OH N-FMOC-LEU-OH N-FMOC-L-LEU N-FMOC-L-LEUCINE NPC 15199 N-ALPHA-FMOC-L-LEUCINE N-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE N-9-FLUORENYLMETHYLOXYCARBONYL-L-LEUCINE N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-LEUCINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LEUCINE PPAR-GAMMA ACTIVATOR N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-L-leucine, (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid N-Fmoc-L-leucine Fmoc-Leu-OH FMoc-Leu-OH >=97.0% Fmoc-L-leucin Fmoc-L-leucine≥ 99.7% (HPLC, Chiral purity) (9H-Fluoren-9-yl)MethOxy]Carbonyl Leu-OH (2R)-2-amino-3-[4-[4-[(2R)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]phenyl]phenyl]propanoic acid FMOC-LEU-OH 250 G FMOC-LEU-OH 100 G L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoicaci Fmoc-Leu-OH Fmoc-Leu-OH FMOC-L-Leucine USP/EP/BP Fmoc-L-leucine, puriss, 99% FMOC-LEU-OH FMOC-L-LEU-OH N-(fluorenyl-9-methoxycarbonyl)leucine FMOC-LEU FMOC-LEUCINE (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid L-LEUCINE-N-FMOC N-(9-Fluorenylmethoxycarbonyl)-L-leucine Fmoc-L-leucine 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid N-Fmoc-L-leucine (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine 35661-60-0 35661-60-6 C21H323NO4 CH32CHCH2CHNHFMOCCOOH