ChemicalBook >> CAS DataBase List >>thielavin A

thielavin A

CAS No.
71950-66-8
Chemical Name:
thielavin A
Synonyms
thielavin A;4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester;Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
CBNumber:
CB61386873
Molecular Formula:
C29H30O10
Molecular Weight:
538.54
MDL Number:
MFCD11111622
MOL File:
71950-66-8.mol
MSDS File:
SDS
Last updated:2024-10-28 23:16:16

thielavin A Properties

Melting point 235-236 °C
Boiling point 850.0±65.0 °C(Predicted)
Density 1.371±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: souble; DMSO: souble; Ethanol: soluble
form White to off-white powder.
pka 2.82±0.28(Predicted)

thielavin A price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21767 Thielavin A ≥95% 71950-66-8 500μg $352 2024-03-01 Buy
Cayman Chemical 21767 Thielavin A ≥95% 71950-66-8 2.5mg $1402 2024-03-01 Buy
Usbiological T5006-50 Thielavin A 71950-66-8 500ug $582 2021-12-16 Buy
TRC T345095 ThielavinA 71950-66-8 1mg $735 2021-12-16 Buy
AK Scientific 2415CB ThielavinA 71950-66-8 2.5mg $1660 2021-12-16 Buy
Product number Packaging Price Buy
21767 500μg $352 Buy
21767 2.5mg $1402 Buy
T5006-50 500ug $582 Buy
T345095 1mg $735 Buy
2415CB 2.5mg $1660 Buy

thielavin A Chemical Properties,Uses,Production

Description

Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 (PGH2; ) and the conversion of PGH2 to PGE2 (; IC50s = 10 and 40 μM, respectively). Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

Uses

Thielavin A acts as an inhibitor of prostagladins biosynthesis.

Uses

The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related thielavin B is a telomerase and cell wall transglycosylation inhibitor.

thielavin A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57423 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8860 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58

View Lastest Price from thielavin A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thielavin A pictures 2024-10-28 Thielavin A
71950-66-8
US $880.00 / μg 10g TargetMol Chemicals Inc.
  • Thielavin A pictures
  • Thielavin A
    71950-66-8
  • US $880.00 / μg
  • TargetMol Chemicals Inc.
thielavin A 4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester 71950-66-8