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ML 161

ML 161 structure

CAS No.: 423735-93-7

Chemical Name:: ML 161

Synonyms: ML 161;CS-1106;Parmodulin 2;ML161, >=98%;ML161;ML-161;ML161 (Parmodulin 2);2-Bromo-N-(3-butanamidophenyl)benzamide;2-BroMo-N-(3-butyraMidophenyl)benzaMide;2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide;Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-

CBNumber:: CB62629267

Molecular Formula:: C17H17BrN2O2

Molecular Weight:: 361.23

MDL Number:: MFCD03063772

MOL File:: 423735-93-7.mol

Last updated:2023-05-18 11:31:16

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ML 161 Properties

Boiling point	465.7±30.0 °C(Predicted)
Density	1.441±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: soluble5mg/mL (clear solution)
pka	12.37±0.70(Predicted)
form	powder
color	white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H410
Precautionary statements	P273-P501
RIDADR	UN 3077 9 / PGIII
WGK Germany	3

ML 161 price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0418	ML-161 ≥98% (HPLC)	423735-93-7	5mg	$111	2024-03-01	Buy
Sigma-Aldrich	SML0418	ML-161 ≥98% (HPLC)	423735-93-7	25mg	$347	2024-03-01	Buy
Cayman Chemical	15179	ML-161 ≥95%	423735-93-7	1mg	$32	2024-03-01	Buy
Cayman Chemical	15179	ML-161 ≥95%	423735-93-7	5mg	$86	2024-03-01	Buy
Cayman Chemical	15179	ML-161 ≥95%	423735-93-7	10mg	$153	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML0418	5mg	$111	Buy
SML0418	25mg	$347	Buy
15179	1mg	$32	Buy
15179	5mg	$86	Buy
15179	10mg	$153	Buy

ML 161 Chemical Properties,Uses,Production

Description

ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC₅₀ value of 0.26 μM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA , U-46619 , or collagen.

Uses

ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation.

Definition

ChEBI: 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide is a member of benzamides.

References

[1]. dockendorff, c., et al., discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the par1 receptor. acs med chem lett, 2012. 3(3): p. 232-237.
[2]. verplank, l., et al., chemical genetic analysis of platelet granule secretion-probe 3, in probe reports from the nih molecular libraries program. 2010, national center for biotechnology information (us): bethesda (md).

ML 161 synthesis

Synthesis of ML 161 from 3-Nitroaniline

ML 161 Preparation Products And Raw materials

Raw materials

N-(3-nitrophenyl)butanamide N-(3-AMINOPHENYL)BUTANAMIDE 3-Nitroaniline 2-Bromobenzoic acid

Preparation Products

ML 161 Suppliers

Global( 92)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10986	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from ML 161 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-04	ML 161 423735-93-7	US $5.00 / KG	1KG	99%	1ton	Career Henan Chemical Co

ML 161
423735-93-7
US $5.00 / KG
99%
Career Henan Chemical Co

ML 161 Spectrum

ML 161(423735-93-7)¹HNMR

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ML 161 2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide 2-BroMo-N-(3-butyraMidophenyl)benzaMide Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]- ML 161 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide ML161;ML-161 ML161, >=98% Parmodulin 2 CS-1106 2-Bromo-N-(3-butanamidophenyl)benzamide ML161 (Parmodulin 2) 423735-93-7 Inhibitors