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4-Fluoro-7-nitrobenzofurazan

4-Fluoro-7-nitrobenzofurazan structure

CAS No.: 29270-56-2

Chemical Name:: 4-Fluoro-7-nitrobenzofurazan

Synonyms: NBD-F;NBD FLUORIDE;4-Fluoro-7-nitro-2,1;4-FLUORO-7-NITROBENZOFURAZAN;4-FLUORO-7-NITROBENZOFUROZAN;4-Fluoro-7-nitrobenzofurazane;NITROBENZOFURAZAN, 4-FLUORO-7-;4-Fluoro-7-nitrobenzofurazan,98%;4-Fluoro-7-nitrobenzofurazan,NBD-F;NBD-F [4-Fluoro-7-nitrobenzofurazan

CBNumber:: CB7255542

Molecular Formula:: C6H2FN3O3

Molecular Weight:: 183.1

MDL Number:: MFCD00010196

MOL File:: 29270-56-2.mol

Last updated:2024-11-19 23:02:33

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4-Fluoro-7-nitrobenzofurazan Properties

Melting point	52-54 °C(lit.)
Boiling point	308.6±45.0 °C(Predicted)
Density	1.6753 (estimate)
Flash point	>230 °F
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	It is soluble in DMSO, DMF, CH3OH, CH3CN and CHCl3.
form	Crystalline Chunks
pka	-5.59±0.50(Predicted)
color	Brown
BRN	1077571
CAS DataBase Reference	29270-56-2(CAS DataBase Reference)
FDA UNII	L5VS78SU5J

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

Hazard Codes

Risk Statements

36/38

Safety Statements

26-36-39

WGK Germany

10-21

HS Code

29349990

NFPA 704

	1
2		0

4-Fluoro-7-nitrobenzofurazan price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	47140	4-Fluoro-7-nitrobenzofurazan BioReagent, suitable for fluorescence, ≥98.0% (HPLC)	29270-56-2	10mg	$470	2024-03-01	Buy
Sigma-Aldrich	47140	4-Fluoro-7-nitrobenzofurazan BioReagent, suitable for fluorescence, ≥98.0% (HPLC)	29270-56-2	50mg	$1920	2024-03-01	Buy
TCI Chemical	A5593	NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole)[for HPLC Labeling] >99.0%(HPLC)	29270-56-2	100mg	$228	2024-03-01	Buy
Alfa Aesar	J61336	4-Fluoro-7-nitrobenzofurazan	29270-56-2	100mg	$508	2024-03-01	Buy
Sigma-Aldrich	F5883	4-Fluoro-7-nitrobenzofurazan ≥98% (elemental analysis)	29270-56-2	5mg	$288	2024-03-01	Buy

Product number	Packaging	Price	Buy
47140	10mg	$470	Buy
47140	50mg	$1920	Buy
A5593	100mg	$228	Buy
J61336	100mg	$508	Buy
F5883	5mg	$288	Buy

4-Fluoro-7-nitrobenzofurazan Chemical Properties,Uses,Production

Chemical Properties

BROWN CRYSTALLINE CHUNKS

Uses

A fluorescence reagent

Uses

4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of functionalized hydroxynaphthofurazan, Spectrophotometric and spectrofluorometric determination of clemastine hydrogen fumarate, loratadine, losartan potassium and ramipril in pharmaceutical formulations. Synthesis of 7-nitrobenzofurazan (NBD)-labeled maleimide, via Diels-Alder reaction. NBD-Cl is widely used to label peptides, proteins, drugs and other biomolecules. It is also a popular derivatizing reagent for HPLC analysis

Purification Methods

Purify it by repeated recrystallisation from pet ether (b 40-60o). On treatment with MeONa in MeOH it gives 4-methoxy-7-nitrobenzo-2-oxa-1,3-diazole m 115-116o. [Nunno et al. J Chem Soc (C) 1433 1970.] It is a very good fluorophore for amino acids [Imai & Watanabe Analyt Chim Acta 130 377 1981], as it reacts with primary and secondary amines to form fluorescent adducts with 470nm and 530nm. It gives a glycine derivative with m 185-187o [Miyano et al. Anal Chim ex em Acta 170 81 1985]. 5-Fluorouracil (5 -fluoropyrimidinedi -2,4 -[1 H ,3 H ]-one) [51 -21 -8] M 130.1, m 282 -2 8 3o(dec), 282-286o(dec), pK 1 8.04, pK 2 13.0. Recrystallise it from H2O or MeOH/Et2O and sublime it at 190-200o/0.1mm or 210-230o/0.5mm. UV: at 265-266nm ( 7070). [Barton et al. J Org max Chem 37 329 1972, Duschinsky & Pleven J Am Chem Soc 79 4559 1957, Beilstein 24 III/IV 1229.]

4-Fluoro-7-nitrobenzofurazan synthesis

Synthesis of 4-Fluoro-7-nitrobenzofurazan from 2,6-Difluoroaniline

4-Fluoro-7-nitrobenzofurazan Preparation Products And Raw materials

Raw materials

1,3-DIFLUORO-2-NITROSO-BENZENE 4-FLUORO-2,1,3-BENZOXADIAZOLE 2,6-Difluoroaniline

Preparation Products

2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)aMino]-2-deoxy-D-glucose

4-Fluoro-7-nitrobenzofurazan Suppliers

Global( 175)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11817	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20342	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58

Supplier	Advantage
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58
Alfa Chemistry	58

View Lastest Price from 4-Fluoro-7-nitrobenzofurazan manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	NBD-F 29270-56-2	US $86.00-53.00 / mg		96.47%	10g	TargetMol Chemicals Inc.
2024-08-24	4-Fluoro-7-nitro-2,1,3-benzoxadiazole 29270-56-2	US $4500.00 / g	1g	97	500 Kg	R&D Scientific Inc.
2024-04-02	4-fluoro-7-nitro-2,1,3-benzoxadiazole 29270-56-2	US $0.00 / g	1g	>95.00%	1g	Xian confluore Biological Technology Co., Ltd.

NBD-F
29270-56-2
US $86.00-53.00 / mg
96.47%
TargetMol Chemicals Inc.

4-Fluoro-7-nitro-2,1,3-benzoxadiazole
29270-56-2
US $4500.00 / g
97
R&D Scientific Inc.

4-fluoro-7-nitro-2,1,3-benzoxadiazole
29270-56-2
US $0.00 / g
>95.00%
Xian confluore Biological Technology Co., Ltd.

4-Fluoro-7-nitrobenzofurazan Spectrum

4-Fluoro-7-nitrobenzofurazan(29270-56-2)MS 4-Fluoro-7-nitrobenzofurazan(29270-56-2)¹HNMR 4-Fluoro-7-nitrobenzofurazan(29270-56-2)¹³CNMR 4-Fluoro-7-nitrobenzofurazan(29270-56-2)IR1

29270-56-2(4-Fluoro-7-nitrobenzofurazan)Related Search:

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4-nitrobenzofurazan 4-Fluoro-7-nitrobenzofurazan fluoro jade

1of4

NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole) [for HPLC Labeling] 4-Fluoro-7-nitrobenzofurazan((D)NBD-F) 4-fluoro-7-nitrobenzo[c][1,2,5]oxadiazole 4-Fluoro-7-nitrobenzofurazan, 98% 25MG 4-Fluoro-7-nitrobenzofurazan 4-Fluoro-7-nitro-2,1,3-benzoxadiazole 4-fluoro-7-nitro-2,1,3-benzooxadiazole 7-Fluoro-4-nitro-2,1,3-benzoxadiazole 7-Nitro-4-fluoro-2,1,3-benzoxadiazole 4-Fluoro-7-nitrobenzofurazan,98% 4-Fluoro-4-nitro-2,1,3-benzoxadiazole 4-Fluoro-7-nitrobenzofurazan,NBD-F 4-Fluoro-7-nitro-2,1 7-FLUORO-4-NITROBENZO-2-OXA-1,3-DIAZOLE 4-FLUORO-7-NITRO-2,1,3-BENZOXADIAZOLE 4-FLUORO-7-NITROBENZ-2-OXA-1,3-DIAZOLE 4-FLUORO-7-NITROBENZOFURAZAN 4-FLUORO-7-NITROBENZOFUROZAN 4-FLUORO-7-NITROBENZOFURAZAN, FOR FLUORE SCENCE NBD FLUORIDE NITROBENZOFURAZAN, 4-FLUORO-7- NBD-F (=4-FLUORO-7-NITRO-2,1,3-BENZOXADIAZOLE) 4-Fluoro-7-nitrobenzofurazane 2,1,3-BENZOXADIAZOLE, 4-FLUORO-7-NITRO- NBD-F [4-Fluoro-7-nitrobenzofurazan] *CAS 29270-56-2* 4-fluoro-4-nitro-1H-2,1,3-benzoxadiazole 4-fluoro-7-nitrobenzo[c][1,2,5]oxadioxle NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole)[for HPLC Labeling]> NBD-F [4-Fluoro-7-nitrobenzofurazan 29270-56-2 2,1,3-Benzoxadiazole, 4-fluoro-7-nitro- 4-Fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) NBD-F 29270-56-2 C6H2FN3O3 Other Fluorescent Labels Fluorescent Labels Fluorescent Probes, Labels, Particles and Stains Detection Biochemicals and Reagents BioChemical Fluorescence Detection (HPLC Labeling Reagents) Amino Group Labeling Reagents for Fluorescence HPLC Mercapto Group Labeling Reagents for Fluorescence HPLC HPLC Labeling Reagents Aromatics Fluorescent Labels & Indicators Heterocycles Amino Group Labeling Reagents for Fluorescence HPLC Analytical Chemistry Fluorescence Detection (HPLC Labeling Reagents) HPLC Labeling Reagents Mercapto Group Labeling Reagents for Fluorescence HPLC