TAXIFOLIN 3-O-RHAMNOSIDE
- CAS No.
- 29838-67-3
- Chemical Name:
- TAXIFOLIN 3-O-RHAMNOSIDE
- Synonyms
- Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Astilbin-RM;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin froM Engelhardtia roxburghiana
- CBNumber:
- CB7507018
- Molecular Formula:
- C21H22O11
- Molecular Weight:
- 450.4
- MDL Number:
- MFCD20274680
- MOL File:
- 29838-67-3.mol
- MSDS File:
- SDS
Melting point | 180 °C (decomp) |
---|---|
Boiling point | 801.1±65.0 °C(Predicted) |
Density | 1.74 |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: soluble1mg/mL, clear, colorless |
pka | 7.34±0.60(Predicted) |
form | A crystalline solid |
color | White to off-white |
InChIKey | ZROGCCBNZBKLEL-MQGABXIONA-N |
SMILES | O([C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@H]1C(C2=C(C=C(O)C=C2O[C@@H]1C1C=CC(O)=C(O)C=1)O)=O |&1:1,4,6,8,10,12,22,r| |
TAXIFOLIN 3-O-RHAMNOSIDE price More Price(43)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A2862 | Astilbin from Engelhardtia roxburghiana ≥98% | 29838-67-3 | 10mg | $199 | 2024-03-01 | Buy |
Cayman Chemical | 28267 | Astilbin | 29838-67-3 | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 28267 | Astilbin | 29838-67-3 | 100mg | $537 | 2024-03-01 | Buy |
Cayman Chemical | 28267 | Astilbin | 29838-67-3 | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 28267 | Astilbin | 29838-67-3 | 25mg | $239 | 2024-03-01 | Buy |
TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Uses,Production
Description
Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.
Uses
Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.
Definition
ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.
TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hovane Phytochemicals Co., Ltd | +86-17340288373 | victor.liu@hovane.com | China | 32 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2993 | 58 |
View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-25 | TAXIFOLIN 3-O-RHAMNOSIDE
29838-67-3
|
US $0.00-0.00 / kg | 1kg | ≥98% HPLC | 1000kg | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2024-11-22 | Astilbin
29838-67-3
|
US $0.00-0.00 / kg | 1kg | 80%HPLC | 1 ton | Hovane Phytochemicals Co., Ltd | ||
2024-11-19 | Astilbin
29838-67-3
|
US $44.00-143.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. |
- TAXIFOLIN 3-O-RHAMNOSIDE
29838-67-3
- US $0.00-0.00 / kg
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
- Astilbin
29838-67-3
- US $0.00-0.00 / kg
- 80%HPLC
- Hovane Phytochemicals Co., Ltd
- Astilbin
29838-67-3
- US $44.00-143.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
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