ChemicalBook >> CAS DataBase List >>TAXIFOLIN 3-O-RHAMNOSIDE

TAXIFOLIN 3-O-RHAMNOSIDE

CAS No.
29838-67-3
Chemical Name:
TAXIFOLIN 3-O-RHAMNOSIDE
Synonyms
Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Astilbin-RM;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin froM Engelhardtia roxburghiana
CBNumber:
CB7507018
Molecular Formula:
C21H22O11
Molecular Weight:
450.4
MDL Number:
MFCD20274680
MOL File:
29838-67-3.mol
MSDS File:
SDS
Last updated:2024-11-19 20:33:22

TAXIFOLIN 3-O-RHAMNOSIDE Properties

Melting point 180 °C (decomp)
Boiling point 801.1±65.0 °C(Predicted)
Density 1.74
storage temp. Sealed in dry,2-8°C
solubility H2O: soluble1mg/mL, clear, colorless
pka 7.34±0.60(Predicted)
form A crystalline solid
color White to off-white
InChIKey ZROGCCBNZBKLEL-MQGABXIONA-N
SMILES O([C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@H]1C(C2=C(C=C(O)C=C2O[C@@H]1C1C=CC(O)=C(O)C=1)O)=O |&1:1,4,6,8,10,12,22,r|

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
HS Code  29389090

TAXIFOLIN 3-O-RHAMNOSIDE price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2862 Astilbin from Engelhardtia roxburghiana ≥98% 29838-67-3 10mg $199 2024-03-01 Buy
Cayman Chemical 28267 Astilbin 29838-67-3 10mg $109 2024-03-01 Buy
Cayman Chemical 28267 Astilbin 29838-67-3 100mg $537 2024-03-01 Buy
Cayman Chemical 28267 Astilbin 29838-67-3 5mg $62 2024-03-01 Buy
Cayman Chemical 28267 Astilbin 29838-67-3 25mg $239 2024-03-01 Buy
Product number Packaging Price Buy
A2862 10mg $199 Buy
28267 10mg $109 Buy
28267 100mg $537 Buy
28267 5mg $62 Buy
28267 25mg $239 Buy

TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Uses,Production

Description

Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.

Definition

ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.

TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 231)Suppliers
Supplier Tel Email Country ProdList Advantage
Hovane Phytochemicals Co., Ltd
+86-17340288373 victor.liu@hovane.com China 32 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5892 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3010 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29882 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2993 58

View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TAXIFOLIN 3-O-RHAMNOSIDE pictures 2024-11-25 TAXIFOLIN 3-O-RHAMNOSIDE
29838-67-3
US $0.00-0.00 / kg 1kg ≥98% HPLC 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Astilbin pictures 2024-11-22 Astilbin
29838-67-3
US $0.00-0.00 / kg 1kg 80%HPLC 1 ton Hovane Phytochemicals Co., Ltd
Astilbin pictures 2024-11-19 Astilbin
29838-67-3
US $44.00-143.00 / mg 99.76% 10g TargetMol Chemicals Inc.
  • Astilbin pictures
  • Astilbin
    29838-67-3
  • US $0.00-0.00 / kg
  • 80%HPLC
  • Hovane Phytochemicals Co., Ltd
  • Astilbin pictures
  • Astilbin
    29838-67-3
  • US $44.00-143.00 / mg
  • 99.76%
  • TargetMol Chemicals Inc.
Taxifolin 3-o-rhamnoside Astilbin Taxifolin 3-O-rhaMnoside Taxifolin 3-rhaMnoside Astilbin froM Engelhardtia roxburghiana Dihydroquercetin 3-rhamnoside (2R,3R)-3-[(6-Deoxy-alpha-L-mannopyranosyloxy)]-2-(3,4-dihydroxy-phenyl)-2,3-dihydro-5,7-dihydroxy-4H-chromen-4-one (2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Astilbin, 98%, from Smilax glabra Roxb. 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3R)- (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chroman-4-one (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihy... Astilbin (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside Astilbin (6CI, 7CI, 8CI) Loastilin Astilbin-RM 29838-67-3 Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract