ChemicalBook >> CAS DataBase List >>BLU9931
BLU9931
- CAS No.
- 1538604-68-0
- Chemical Name:
- BLU9931
- Synonyms
- BLU;BLU9931;LM-3610;CS-1699;BLU-9931;BLU 9931;LM-3610; BLU9931;BLU 9931;BLU-9931;BLU-9931;BLU 9931;BLU9931;BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor
- CBNumber:
- CB82741679
- Molecular Formula:
- C26H22Cl2N4O3
- Molecular Weight:
- 509.38
- MDL Number:
- MFCD28900729
- MOL File:
- 1538604-68-0.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Density | 1.361±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | ≥50.9 mg/mL in DMSO; insoluble in H2O; ≥2.53 mg/mL in EtOH with gentle warming and ultrasonic |
| form | Powder |
| pka | 13.15±0.70(Predicted) |
| color | Off-white to light yellow |
| FDA UNII | FQK825B5DX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H227 | |||||||||
| Precautionary statements | P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235 | |||||||||
| NFPA 704 |
|
BLU9931 price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18405 | BLU9931 ≥98% | 1538604-68-0 | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 18405 | BLU9931 ≥98% | 1538604-68-0 | 5mg | $216 | 2024-03-01 | Buy |
| Cayman Chemical | 18405 | BLU9931 ≥98% | 1538604-68-0 | 10mg | $380 | 2024-03-01 | Buy |
| Cayman Chemical | 18405 | BLU9931 ≥98% | 1538604-68-0 | 25mg | $711 | 2024-03-01 | Buy |
| AK Scientific | 4064DW | N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]-3-methylphenyl]prop-2-enamide | 1538604-68-0 | 10mg | $185 | 2021-12-16 | Buy |
BLU9931 Chemical Properties,Uses,Production
Definition
BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity. BLU9931 makes a covalent bond with Cys552 within the ATP-binding pocket of FGFR4, which is not present in FGFR1-3. BLU9931 inhibited gastric cancer cell growth in a transplanted mouse model[1].
References
[1] Norihiko Sasaki. “FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.” Cancers (2020).
BLU9931 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 136)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
View Lastest Price from BLU9931 manufacturers
1538604-68-0(BLU9931)Related Search:
BLU 9931
BLU9931
BLU-9931
LM-3610
LM-3610; BLU9931
N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)-3-methylphenyl)acrylamide
N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-2-propenamide
2-Propenamide,N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-
BLU 9931;BLU-9931
BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor
BLU
CS-1699
BLU-9931;BLU 9931;BLU9931
1538604-68-0
C26H22Cl2N4O3
Inhibitors