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MYOSMINE

CAS No.
532-12-7
Chemical Name:
MYOSMINE
Synonyms
Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-;MYOSIME;yosmine;MYSOMINE;MYOSMINE;Myosming;Brn 0119254;MYOSMINE(RG);Masmin, Masmin;WIDELY MYOSMINE
CBNumber:
CB9354452
Molecular Formula:
C9H10N2
Molecular Weight:
146.19
MDL Number:
MFCD00052019
MOL File:
532-12-7.mol
MSDS File:
SDS
Last updated:2025-03-06 08:32:39

MYOSMINE Properties

Melting point 42-44°C
Boiling point 82-83°C 0,5mm
Density 1.12±0.1 g/cm3(Predicted)
Flash point 82-83°C/0.5mm
storage temp. 2-8°C
solubility Methanol (Slightly), Water (Sparingly)
form Solid
pka pK1:5.26 (25°C)
color Light Beige to Dark Yellow
BRN 119254
Stability Moisture, Temperature Sensitive
LogP 0.730 (est)
CAS DataBase Reference 532-12-7(CAS DataBase Reference)
FDA UNII 9O0A545W4L
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UT7660000
HazardClass  IRRITANT, IRRITANT-HARMFUL
HS Code  29399990
NFPA 704
1
2 0

MYOSMINE price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M8765 Myosmine ≥98% 532-12-7 100mg $112 2024-03-01 Buy
Sigma-Aldrich PHR3062 Nicotine Related Compound D certified reference material, pharmaceutical secondary standard 532-12-7 50MG $507 2024-03-01 Buy
Sigma-Aldrich 1463359 Myosmine 532-12-7 20mg $1450 2024-03-01 Buy
Alfa Aesar L11886 Myosmine, 98%, may contain up to 2% water 532-12-7 100mg $78 2024-03-01 Buy
Alfa Aesar L11886 Myosmine, 98%, may contain up to 2% water 532-12-7 500mg $282 2024-03-01 Buy
Product number Packaging Price Buy
M8765 100mg $112 Buy
PHR3062 50MG $507 Buy
1463359 20mg $1450 Buy
L11886 100mg $78 Buy
L11886 500mg $282 Buy

MYOSMINE Chemical Properties,Uses,Production

Description

The alkaloids found in tobacco smoke may be separated into those which are volatile in steam and those which are non-volatile. Myosmine occurs in the former group and, although only present in small quantities, is the most fully investigated of these bases. The alkaloid is normally obtained as an oily liquid which may be crystallized. It is optically inactive and readily soluble in light petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which, on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0- 17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole (picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of several products formed when nicotine is dehydrogenated over prepared quartz at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C.

Chemical Properties

Light Yellow Powder

Uses

Tobacco alkaloid

Reactant for:
Nitrosation reactions
Peroxidation reaction with hydrogen peroxide

Uses

mitogen

Uses

Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source.

Definition

ChEBI: Myosmine is a member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. It has a role as a plant metabolite, an EC 1.14.14.14 (aromatase) inhibitor and a mutagen. It is a pyrroline and a pyridine alkaloid.

Synthesis Reference(s)

Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094
The Journal of Organic Chemistry, 37, p. 1635, 1972
Tetrahedron Letters, 8, p. 5185, 1967

References

Spath, Wenusch, Zajic., Ber., 69, 393 (1936)
Woodward, Eisner, Haines., ibid, 69, 7S7 (1936)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)

93-60-7
117593-76-7
532-12-7
Synthesis of MYOSMINE from Methyl nicotinate and 1-(1-buten-1-yl)-2-Pyrrolidinone
Global( 238)Suppliers
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View Lastest Price from MYOSMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MYOSMINE pictures 2025-04-23 MYOSMINE
532-12-7
US $10.00 / KG 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
MYOSMINE pictures 2025-04-21 MYOSMINE
532-12-7
US $0.00-0.00 / kg 1kg 98 1000 Wuhan Circle Star Chem-medical Technology Co.,Ltd
MYOSMINE pictures 2025-03-21 MYOSMINE
532-12-7
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
  • MYOSMINE pictures
  • MYOSMINE
    532-12-7
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • MYOSMINE pictures
  • MYOSMINE
    532-12-7
  • US $0.00-0.00 / kg
  • 98
  • Wuhan Circle Star Chem-medical Technology Co.,Ltd
  • MYOSMINE pictures
  • MYOSMINE
    532-12-7
  • US $0.00 / KG
  • 99%
  • Hebei Mujin Biotechnology Co.,Ltd

MYOSMINE Spectrum

3-[1-PYRROLIN-2-YL]PYRIDINE 3-(3,4-DIHYDRO-2H-PYRROL-5-YL)PYRIDINE 3-(4,5-DIHYDRO-3H-PYRROL-2-YL)PYRIDINE MYOSIME MYOSMINE MYSOMINE MYOSMINE(RG) PYRIDINE,3-(1-PYRROLIN-2-YL)- Brn 0119254 Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)- (9ci) Myosmine, 98%, may contain up to 2% water 2-(3-Pyridyl)-1-pyrroline 3-(1-pyrrolin-2-yl)-pyridin MyosMine, froM Nicotiana tabacuM L. Nicotine Related Compound D (20 mg) (3-(4,5-dihydro-3H-pyrrol-2-yl)pyridine fumarate) Nicotine EP Impurity D (myosmine ) Myosmine, 98%, from Nicotiana tabacum L. NICOTINE RELATED COMPOUND D Nicotine EP Impurity D Nicotine Related Compound D (20 mg) Nicotine EP Impurity D/ Nicotine Related Compound D (Myosmine) WIDELY MYOSMINE Myosming yosmine Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)- Nicotine USP Related Compound D 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine (Myosmine) 3-(4,5-dihydro-3H-pyrrol-2-yl)pyridine (myosmine) Nicotine Intermediates MYOSMINE Masmin, Masmin Acamprosate Impurity 7 Myosmine, 10 mM in DMSO 532-12-7 Pyridines Heterocyclic Building Blocks Building Blocks C9 to C46 Amines Alkaloids Nicotine Derivatives Heterocycles 532-12-7