ChemicalBook >> CAS DataBase List >>tert-Butyl carbazate
tert-Butyl carbazate
- CAS No.
- 870-46-2
- Chemical Name:
- tert-Butyl carbazate
- Synonyms
- tert-butyl hydrazinecarboxylate;carbazate;BOC-NHNH2;BOC-HYDRAZINE;T-BUTYLCARBAZATE;tert-Butyl N-aminocarbamate;HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER;BOC-HYDRAZIDE;TERT-BUTOXYCARBONYL HYDRAZIDE;T-BOC-HYDRAZIDE
- CBNumber:
- CB9686391
- Molecular Formula:
- C5H12N2O2
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00007593
- MOL File:
- 870-46-2.mol
- MSDS File:
- SDS
Last updated:2024-11-01 18:09:03
| Melting point | 39-42 °C (lit.) |
|---|---|
| Boiling point | 63-65 °C/0.1 mmHg (lit.) |
| Density | 1.02 |
| refractive index | 1.4496 (estimate) |
| Flash point | 197 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in ethanol and methanol. |
| pka | 10.74±0.20(Predicted) |
| form | Crystalline Lumps |
| color | White to slightly yellow |
| Sensitive | Moisture Sensitive |
| BRN | 1756967 |
| InChIKey | DKACXUFSLUYRFU-UHFFFAOYSA-N |
| CAS DataBase Reference | 870-46-2(CAS DataBase Reference) |
| EPA Substance Registry System | Hydrazinecarboxylic acid, 1,1-dimethylethyl ester (870-46-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228 | |||||||||
| Precautionary statements | P210 | |||||||||
| Hazard Codes | T-F,T,F | |||||||||
| Risk Statements | 48-36/37/38-24/25-11 | |||||||||
| Safety Statements | 45-36/37/39-16-24/25 | |||||||||
| RIDADR | 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29280090 | |||||||||
| NFPA 704 |
|
tert-Butyl carbazate price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B91005 | tert-Butyl carbazate 98% | 870-46-2 | 5g | $38.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | B91005 | tert-Butyl carbazate 98% | 870-46-2 | 25g | $79.4 | 2024-03-01 | Buy |
| Alfa Aesar | A12383 | tert-Butyl carbazate, 98+% | 870-46-2 | 25g | $74.2 | 2024-03-01 | Buy |
| Alfa Aesar | A12383 | tert-Butyl carbazate, 98+% | 870-46-2 | 100g | $126.65 | 2024-03-01 | Buy |
| Sigma-Aldrich | B91005 | tert-Butyl carbazate 98% | 870-46-2 | 100g | $148 | 2024-03-01 | Buy |
tert-Butyl carbazate Chemical Properties,Uses,Production
Chemical Properties
White to pale yellow lumps
Uses
Starting material for preparing BOC-azide, a reagent to introduce the BOC amino protection.
Uses
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.
Synthesis Reference(s)
Journal of the American Chemical Society, 82, p. 2725, 1960 DOI: 10.1021/ja01496a018
Chemical and Pharmaceutical Bulletin, 18, p. 217, 1970 DOI: 10.1248/cpb.18.217
Purification Methods
Distil it in a Claisen flask with a water or oil bath at ca 80o. After a couple of drops have distilled, the carbazate is collected as an oil which solidifies to a snow white solid. It can be crystallised with 90% recovery from a 1:1 mixture of pet ether (b 30-60o) and pet ether (b 60-70o). [Carpino et al. Org Synth Coll Vol V 166 1973, Caprino et al. Org Synth 44 20 1964, Beilstein 3 IV 175.]
tert-Butyl carbazate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
PYRIDIN-2-YLMETHYL-HYDRAZINE
PYRIDIN-3-YLMETHYL-HYDRAZINE
(2-METHOXY-1-METHYL-ETHYL)-HYDRAZINE
PYRIDIN-4-YLMETHYL-HYDRAZINE
CYCLOBUTYLHYDRAZINE
1of3
Global( 627)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GenChem & GenPharm (Changzhou) Co., Ltd. | +86-86020003 +86-18861157602 | sales03@genchem.cn | China | 104 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2158 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
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| Hebei Weimiao Import and Export Trade Co., Ltd. | +86-19948166995 +86-19948166995 | sale01@hbweimiao.com | China | 76 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
| Sigma Audley | +86-15937194204 +86-18126314766 | nova@sh-teruiop.com | China | 467 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
View Lastest Price from tert-Butyl carbazate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-25 | tert-Butyl carbazate
870-46-2
|
US $6.00 / KG | 1KG | 99% | 20TONS | Hebei Longbang Technology Co., Ltd | |
 |
2024-11-22 | Tert-Butyl carbazate
870-46-2
|
US $30.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-11-01 | tert-Butyl carbazate
870-46-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
-
- tert-Butyl carbazate
870-46-2
- US $6.00 / KG
- 99%
- Hebei Longbang Technology Co., Ltd
-
- Tert-Butyl carbazate
870-46-2
- US $30.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- tert-Butyl carbazate
870-46-2
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
870-46-2(tert-Butyl carbazate)Related Search:
TERT-BUTOXYCARBONYLHYDRAZINE
TERT-BOC-HYDRAZIDE
TERT-BUTYLOXYCARBAZATE
T-BUTOXYCARBONYL HYDRAZIDE
T-BUTYLOXYCARBONYL-HYDRAZIDE
tert-Butyl hydrazinocarboxylate
tert-Butylcarbazate,98+%
BOC-HYDRAZIDE 98%
TERT-BUTYL CARBAZATE 99%
tert-Butyl carbazate, 97+%
tert-Butoxycarbonyl hydrazide, Boc-hydrazide
N-T-BUTOXYCARBONYL-HYDRAZIDE
CustoM-Made product
tert-Butyl carbaza
1-Boc hydrazine
tert-Butyl carbazate
Hydrazinecarboxylic acid-1,1-dimethyl ester
BOC-Hydrazine tert-Butyl carbazate
Tert-Cutyl Carbazate
tert-Butyl hydrazinoformate
Boc-hydrazide≥ 99% (GC)
Carbazic acid 1,1-dimethylethyl ester
N-Aminocarbamic acid tert-butyl ester
tert-Butyl carbazate,99%
LABOTEST-BB LT00053500
Boc-hydrazine
tert-Butoxycarbonylhydrazine
Carbazic Acid tert-Butyl Ester
TERT-BUTYL CARBAZATE FOR SYNTHESIS
hydrazinecarboxylicacid,1,1-dimethylethylester
AKOS B028820
Tert-Butyl carbazateCAS
BOC-hydrazide（Tert-Butyl carbazate）
tert-Butyl carbazate,tert-Butoxycarbonyl hydrazide, Boc-hydrazide
tert-Butyl carbazate
tert-Butyl carbazate, 99% 100GR
tert-Butyl carbazate, 99% 500GR
+-BUTYL CARBAZATE
CARBONIC ACID TERT-BUTYL ESTER HYDRAZIDE
CARBAZINIC ACID TERT-BUTYL ESTER
CARBAZIC ACID TERT-BUTYL ESTER
Baloxavir Impurity 35
ert-Butyl carbazate
tert-Butyl carbazate T-BOC-HYDRAZIDE
tert-Butyl carbazate solution
tert-Butyl Carbazate >
tert-Butyl carbazate, 99%, for synthesis
1-Boc hydrazine(BOC-NHNH2)
tert-Butyl Carbazate (TBC)
tert-Butyl Carbazate extrapure, 98%
TERT-BUTOXYCARBONYL HYDRAZIDE
tert-butyloxycarbonyl-hydrazide
T-BOC-HYDRAZIDE
T-BUTYLCARBAZATE
tert-Butyl N-aminocarbamate
tert-butyl hydrazinecarboxylate
BOC-HYDRAZIDE
BOC-HYDRAZINE
BOC-NHNH2
carbazate