Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Organic Chemistry >Amides >N-Methyl-1H-Indole-5-EthaneSulphonamide

N-Methyl-1H-Indole-5-EthaneSulphonamide

N-Methyl-1H-Indole-5-EthaneSulphonamide Structure
CAS No.
98623-50-8
Chemical Name:
N-Methyl-1H-Indole-5-EthaneSulphonamide
Synonyms
2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide;ratriptanImpurity5;N-Methyl-1H-Indole-5-EthaneSulphomide;N-Methyl-1H-indole-5-ethanesulfonamide;N-Methyl-1H-Indole-5-EthaneSulphonamide;1H-Indole-5-ethanesulfonamide, N-methyl-;2-(1H-indol-5-yl)-N-MethylethanesulfonaMide;N-Methyl-1H-indole-5-ethanesulfonamide, >=98%;2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide;N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide)
CBNumber:
CB01023956
Molecular Formula:
C11H14N2O2S
Molecular Weight:
238.31
MOL File:
98623-50-8.mol
MSDS File:
SDS
Modify Date:
2023/10/16 9:41:38
Request For Quotation

N-Methyl-1H-Indole-5-EthaneSulphonamide Properties

Melting point 124-125°C
Boiling point 458.4±47.0 °C(Predicted)
Density 1.316±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 11.52±0.40(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P305+P351+P338

N-Methyl-1H-Indole-5-EthaneSulphonamide Chemical Properties,Uses,Production

Uses

N-Methyl-1H-indole-5-ethanesulfonamide is used as a reagent in the synthesis of Naratriptan Hydrochloride (N378730); a triptan drug used for the treatment of migraine headaches.

General Description

N-Methyl-1H-Indole-5-EthaneSulphonamide, also known as 2-(1H-Indol-5-yl)-N-methylethanesulfonamide, is a white solid.

Synthesis

At 40-45 ℃ (hydrogen pressure: 3-4 kg/cm2), 2-(3-Phenylsulf-anyl-1H-indol-5-yl)-ethanesulfonic acidmethylamide (14) (5 g, 0.014 mol) was hydrogenated in ethanol: water (7:3) (40 ml) in an autoclave for 10 h. After that, the reaction mass was cooled to room temperature, followed by removing the catalyst through filtering. The filtrate was distilled out to get N-Methyl-1H-Indole-5-EthaneSulphonamide. N-Methyl-1H-Indole-5-EthaneSulphonamide

N-Methyl-1H-Indole-5-EthaneSulphonamide Preparation Products And Raw materials

Raw materials

1H-Indole-2-carboxylic acid, 5-[2-[(methylamino)sulfonyl]ethyl]- 1H-Indole-5-ethanesulfonamide, N-methyl-3-(phenylthio)- 1-AMinocyclobutane-1-carbonitrile 2-(4-AMino-3-iodophenyl)-N-MethylethanesulfonaMide 4-AMINO-N-METHYLBENZENETHANASULFONAMIDE
1305334-90-0 Methylamine
chevron_left

1of2

chevron_right

Preparation Products

3,4-Dihydro Naratriptan (Naratriptan Impurity B)

N-Methyl-1H-Indole-5-EthaneSulphonamide Suppliers

Global( 67)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
VGS SYNTHESIS PRIVATE LIMITED +91-9866975588 +91-9866975588 Hyderabad, India 1818 58 Inquiry
Stereokem Pvt Ltd +91-4029706929 +91-9394224843 Telangana, India 350 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
Sibram Pharmaceutical +91-8655777550 +91-8655777550 Maharashtra, India 244 58 Inquiry
Manus Aktteva Biopharma LLP +91 79 26463394 Gujarat, India 275 58 Inquiry
Stereokem, Inc. 500039 New Delhi, India 293 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shanghai Boc Chemical Co., Ltd. 021-34975602; +8618721111801 China 138 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21675 55 Inquiry
Supplier Advantage
VGS SYNTHESIS PRIVATE LIMITED 58
Stereokem Pvt Ltd 58
Rivashaa Agrotech Biopharma Pvt. Ltd. 58
Sibram Pharmaceutical 58
Manus Aktteva Biopharma LLP 58
Stereokem, Inc. 58
CLEARSYNTH LABS LTD. 58
Shanghai Boc Chemical Co., Ltd. 58
Capot Chemical Co.,Ltd. 60
Henan Tianfu Chemical Co.,Ltd. 55

98623-50-8(N-Methyl-1H-Indole-5-EthaneSulphonamide)Related Search:

N-METHYL-N-[3-(TRIFLUOROMETHYL)BENZYL]AMINE N-METHYL-2-NITROBENZYLAMINE 3-METHOXY-N-METHYLBENZYLAMINE 97 N-METHYL-N-[4-(TRIFLUOROMETHYL)BENZYL]AMINE N-Methyl-3,4-dimethylbenzylamine
1-METHYL-1H-INDOLE-2-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER N-Methyl-2,3-difluorobenzylaMine N-Methyl-2-thiazolamine (4-FLUORO-BENZYL)-METHYL-AMINE 4-(Methylaminomethyl)benzonitrile
(4-BROMOBENZYL)METHYLAMINE N-methylbiphenyl-2-amine N-Methyl-1-amino-hex-5-ene N-Methyl-N-(4-methylbenzyl)amine N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE
Naratriptan Hydrochloride N-Methyl-1H-Indole-5-EthaneSulphonamide Naratriptan
chevron_left

1of4

chevron_right
N-Methyl-1H-Indole-5-EthaneSulphonamide N-Methyl-1H-indole-5-ethanesulfonamide 2-(1H-indol-5-yl)-N-MethylethanesulfonaMide N-Methyl-1H-indole-5-ethanesulfonamide, >=98% N-Methyl-1H-Indole-5-EthaneSulphomide 1H-Indole-5-ethanesulfonamide, N-methyl- 2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide 2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide ratriptanImpurity5 N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide) 98623-50-8