Naratriptan Hydrochloride
- CAS No.
- 143388-64-1
- Chemical Name:
- Naratriptan Hydrochloride
- Synonyms
- Naramig;Amerge.;GR-85548A;Nariptan Hydrochloride;Naratriptan Nitrate USP;GR-85548A hydrochloride;Naratriptan Hydrochloride;Naratryptan hydrochloride;Naratriptan monohydrochloride;Naratriptan HCl (GR-85548A HCl)
- CBNumber:
- CB4500391
- Molecular Formula:
- C17H25N3O2S.ClH
- Molecular Weight:
- 371.93
- MOL File:
- 143388-64-1.mol
- Modify Date:
- 2023/6/8 9:02:06
Naratriptan Hydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N1415 | Naratriptan hydrochloride ≥98% (HPLC) | 143388-64-1 | 10MG | ₹8746.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N1415 | Naratriptan hydrochloride ≥98% (HPLC) | 143388-64-1 | 50MG | ₹32929.65 | 2022-06-14 | Buy |
| TCI Chemicals (India) | N1153 | Naratriptan Hydrochloride | 143388-64-1 | 50MG | ₹6400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N1153 | Naratriptan Hydrochloride | 143388-64-1 | 250MG | ₹19800 | 2022-05-26 | Buy |
Naratriptan Hydrochloride Chemical Properties,Uses,Production
Description
Naramig was launched in Germany, Sweden and the UK for use in migraine. It is chemically available via a number of related synthetic routes all having about three steps starting from 5-bromoindole. It is a new serotonin 5-HT1B/1D receptor antagonist with modest affinity for 5-HT1a, and very weak affinity for 5-HT3 receptors. It has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors, dopamine, neurokinin NK1, and opiate receptors. It mediates vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It has a 6- and 3-fold greater affinity for 5-HT1B, and 5-HT1D, receptors, respectively, than sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig had no clinical effects on blood pressure or heart rate, had a long duration of action with very good tolerability, and has high oral bioavailability.
Chemical Properties
Beige Solid
Uses
Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches
Naratriptan Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| USV Pvt Ltd | +91-2267861111 +91-2225564048 | Maharashtra, India | 36 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Nosch Labs Pvt Ltd | +91-4048557474 +91-9948222287 | Hyderabad, India | 58 | 58 | Inquiry |
| Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.) | +91-4428244254 +91-4428244254 | Tamil Nadu, India | 28 | 58 | Inquiry |
| Stereokem Pvt Ltd | +91-4029706929 +91-9394224843 | Telangana, India | 350 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Ind Swift Laboratories Ltd | +91-1126226140 +91-1126226140 | New Delhi, India | 26 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
143388-64-1(Naratriptan Hydrochloride)Related Search:
1of4
chevron_right