Naratriptan

Naratriptan Structure
CAS No.
121679-13-8
Chemical Name:
Naratriptan
Synonyms
Naratriptan;Naratriptan1;Naratriptane;Naratriptan(Amerge);AMERGE; NARAMIG; GR-85548A;N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide;N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide;N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide;Inhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor,Naratriptan;NaratriptanQ: What is Naratriptan Q: What is the CAS Number of Naratriptan Q: What is the storage condition of Naratriptan
CBNumber:
CB1874790
Molecular Formula:
C17H25N3O2S
Molecular Weight:
335.46
MOL File:
121679-13-8.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

Naratriptan Properties

Melting point 170-171°
Boiling point 541.3±60.0 °C(Predicted)
Density 1.227±0.06 g/cm3(Predicted)
pka 11.52±0.40(Predicted)

Naratriptan Chemical Properties,Uses,Production

Uses

Naratriptan is a triptan drug that is used for the treatment of migraine headaches.

General Description

Naratriptan, the third triptan approved in 1998, is one of themost lipophilic triptans marketed to date. It has a much improvedbioavailability (63% in men and 74% in women), agreater affinity for 5-HT1B/1D receptors (3–6 times), and alower recurrence rate than sumatriptan because of its muchlonger elimination half-life. Naratritan also has a favorableCNS side effect profile when compared with sumatriptanor zolmitriptan because of its metabolic stability,thereby lacking a N-demethylated active metabolite and asignificant renal excretion ( 70% of naratriptan is excretedunchanged and the rest of the administered dose is degradedvia several CYP isozymes).

Naratriptan Preparation Products And Raw materials

Global( 98)Suppliers
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Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry

Naratriptan Spectrum

Naratriptan Naratriptane N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide Naratriptan(Amerge) N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide Naratriptan1 AMERGE; NARAMIG; GR-85548A N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide NaratriptanQ: What is Naratriptan Q: What is the CAS Number of Naratriptan Q: What is the storage condition of Naratriptan Inhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor,Naratriptan 121679-13-8 21679-13-8 API Indoline & Oxindole