ENPROFYLLINE

ENPROFYLLINE Structure
CAS No.
41078-02-8
Chemical Name:
ENPROFYLLINE
Synonyms
nilyph;d-4028;Enprofilina;ENPROFYLLINE;Enprofyllilie;ENPROPHYLLINE;Enprofyllinum;3-PROPYLXANTHINE;3-Propylxanthfine;3-N-PROPYLXANTHINE
CBNumber:
CB0108540
Molecular Formula:
C8H10N4O2
Molecular Weight:
194.19
MOL File:
41078-02-8.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

ENPROFYLLINE Properties

Melting point 287-289 °C
Density 1.38 g/cm3
storage temp. 2-8°C
solubility DMSO: soluble
form solid
pka 10.26±0.20(Predicted)
color white
CAS DataBase Reference 41078-02-8

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H332-H302-H312
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
RTECS  UO8439700
NFPA 704
0
3 0

ENPROFYLLINE Chemical Properties,Uses,Production

Description

3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 μM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 μM). Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.

Uses

Enprofylline is a xanthine lacking adenosine receptor antagonism.

Definition

ChEBI: Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic n uropathy.

ENPROFYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9624 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503259 +86-19930503259 China 18435 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Hebei Fengmu Trading Co., Ltd. +8613393234347 China 2996 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry

ENPROFYLLINE Spectrum

nilyph 3,9-dihydro-3-propyl-purine-2,6-dione 3-Propylxanthfine Enprofyllilie 3-propyl-7H-purine-2,6-dione 3-propyl-7H-purine-2,6-quinone 1H-Purine-2,6-dione, 3,9-dihydro-3-propyl- ENPROPHYLLINE 3-Propyl-1H-purine-2,6(3H,7H)-dione 3-N-PROPYLXANTHINE 3-PROPYLXANTHINE ENPROFYLLINE 3,7-dihydro-3-propyl-1h-purine-2,6-dione 3-Propyl 3,7-dihydro-1H-purine-2,6-dione 3-Propyl-7H-purine-2,6(1H,3H)-dione 3,7-dihydro-3-propyl-1h-purine-6-dione d-4028 Enprofilina Enprofyllinum 3-propyl-2,3,6,7-tetrahydro-1H-purin-2,6-dione chronic obstructive pulmonary,interleukin-8,A2B receptor antagonist,phosphodiesterase inhibitor,Enprofylline,Adenosine Receptor,Adenosine,inhibit,asthma,Inhibitor,phospholipase C,P1 receptor,Phosphodiesterase (PDE) 3,9-Dihydro-3-propyl-1H-purin-2,6-dione 41078-02-8