Exendin-3 (9-39) amide
- CAS No.
- 133514-43-9
- Chemical Name:
- Exendin-3 (9-39) amide
- Synonyms
- EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
- CBNumber:
- CB0109941
- Molecular Formula:
- C149H234N40O47S
- Molecular Weight:
- 3369.76
- MOL File:
- 133514-43-9.mol
- Modify Date:
- 2024/7/2 8:54:55
Density | 1.51 |
---|---|
RTECS | LF2460000 |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | H2O : 50 mg/mL (14.84 mM; Need ultrasonic) |
form | Solid |
color | Off-white to pale purple |
Water Solubility | Soluble in water at 1mg/ml |
InChIKey | WSEVKKHALHSUMB-UHFFFAOYSA-N |
Exendin-3 (9-39) amide Chemical Properties,Uses,Production
Description
Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.
Uses
Biological probe.
General Description
Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.
Exendin-3 (9-39) amide Preparation Products And Raw materials
Raw materials
Preparation Products
Exendin-3 (9-39) amide Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8828 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 999 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | China | 2996 | 58 | Inquiry |
Alfa Chemistry | +1-5166625404 | United States | 21317 | 58 | Inquiry |
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