ChemicalBook > Product Catalog >Pharmaceutical intermediates >(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one

CAS No.: 85175-59-3

Chemical Name:: (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one

Synonyms: 7,8-Dimethoxy-3-(3-chloropropyl)-1,3-dihydro-2H-3-benzazepin-2-one;3-(3-chloropropyl)-7,8-diMethoxy-1H-benzo[d]azepin-2(3H)-one;3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one;-2-one;Ivabradin-1;Ivabradine Impurity f;Ivabradine Impurity c;Ivabradine Impurity 64;Ivabradine intermediate2;(Z)-3-(3-chloropropyl)-7

CBNumber:: CB01509856

Molecular Formula:: C15H18ClNO3

Molecular Weight:: 295.76

MOL File:: 85175-59-3.mol

MSDS File:: SDS

Modify Date:: 2024/5/24 15:44:31

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(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one Properties

Melting point	100-102 °C(Solv: ethanol (64-17-5))
Boiling point	484.1±45.0 °C(Predicted)
Density	1.191±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	-1.23±0.20(Predicted)
color	White to Off-White

SAFETY

Risk and Safety Statements

Signal word	Danger
Hazard statements	H332-H312-H302
Precautionary statements	P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
HS Code	29339900

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one Chemical Properties,Uses,Production

Description

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one is the side chain of ivabradine hydrochloride. Ivabradine and its medicinal salts, especially its hydrochloride, have very important pharmacological and therapeutic properties, especially, in slowing down the heart rate. Relating compounds can be used to treat or prevent various clinical myocardial ischemia conditions, such as angina pectoris, myocardial infarction and related rhythm disorders, various pathologies involving rhythm disorders, especially supraventricular rhythm disorders.

Uses

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one is an organic compound which can be used as pharmaceutical intermediates.

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one Preparation Products And Raw materials

Raw materials

7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one 1-Bromo-3-chloropropane

Preparation Products

7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one Suppliers

Global( 228)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TAGOOR LABORATORIES PVT LTD	+919700187008	AndhraPradesh, India	93	58	Inquiry
Urantiis Pharmaceuticals Private Limited	+918790703567	AndhraPradesh, India	80	58	Inquiry
Rampex Labs Private Limited	+91 9168074433	Telangana, India	71	58	Inquiry
Molkem Chemicals	+91-917228022464 +91-7228022464	Ahmedabad, India	138	58	Inquiry
SKVen Technologies Pvt.Ltd.	+91-7032295152 +91-7032295152	Hyderabad, India	81	58	Inquiry
Lorven therapeutics Pvt Ltd	+91-8884110005 +91-8884110005	Hyderabad, India	110	58	Inquiry
Greenovel life sciences Pvt Ltd		Hyderabad, India	138	58	Inquiry
KARPSCHEM LABORATORIES	+91-7249203006 +91-7249203006	Maharashtra, India	786	58	Inquiry
Glenfin Chemicals Pvt Ltd	+91-9923430013 +91-9323802458	Maharashtra, India	63	58	Inquiry
Opulant Pharmaceuticals Pvt Ltd	+91-8105130349 +91-8105130349	Telangana, India	66	58	Inquiry

Supplier	Advantage
TAGOOR LABORATORIES PVT LTD	58
Urantiis Pharmaceuticals Private Limited	58
Rampex Labs Private Limited	58
Molkem Chemicals	58
SKVen Technologies Pvt.Ltd.	58
Lorven therapeutics Pvt Ltd	58
Greenovel life sciences Pvt Ltd	58
KARPSCHEM LABORATORIES	58
Glenfin Chemicals Pvt Ltd	58
Opulant Pharmaceuticals Pvt Ltd	58

What is (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one?
3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one is a reactant used in the synthesis of Zatebradine analogues as pot....
Sep 8，2021

85175-59-3((Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one)Related Search:

3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 7-DeMethyl Ivabradine 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one N-DeMethyl Ivabradine Hydrochloride 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one)

C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE (3,4-Dimethoxyphenyl)acetic acid Hydroxy Ivabradine N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide 8-DeMethyl Ivabradine

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one 4,5-Dimethoxy-1-cyanobenzocyclobutane

Ivabradine Impurity 70 1204612-29-2 3,4-dimethoxy-N-methylbenzamide

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(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one ,8-Dimethoxy-3-(3-chloropropyl)-1,3-dihydro-2H-3-benzazepin-2-one 3-(3-Chloro-propyl)-7,8-dimethoxy-1,3-dihydro-benzo[d]azepin-2-one 3-(3-chloropropyl)-7,8-diMethoxy-2,3-dihydro-1H-3-benzazepin-2-one 3-(3-Chloropropyl)-7,8-diMethoxy-1H-3-benzazepin-2(3H)-one 2H-3-Benzazepin-2-one, 3-(3-chloropropyl)-1,3-dihydro-7,8-diMethoxy- 3-(3-Chloropropyl)-1,3-dihydro-7,8-diMethoxy-2H-3- 3-(3-chloropropyl)-1,3-dihydro-7,8-diMethoxy-2H-3-Benzazepin-2-one(For Ivabradine) Ivabradine Impurity c Ivabradine Impurity f 3-(3-chloropropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one 3-(3-chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2-one 7,8-Dimethoxy-3-(3-chloropropyl)-1,3-dihydro-2H-3-benzazepin-2-onezazepin-2-one Ivabradine intermediate2 3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-be Ivabradine related compound 4 Ivabradin-1 (Z)-3-(3-chloropropyl)-7 8-diethyl-1H-benzo[d] azepin-2 (3H)-one Ivabradine Impurity 64 7,8-dimethoxy-3- (3-chloropropyl) - 1,3-dihydro-2h-3-benzoazepine-2-one AZEPIN-2 (3H) - (Z) -3- (3-chloropropyl) -7, 8-diethyl-1H - benzo [D] azepin-2 (3H) - (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H) 3-(3-CHLOROPROPYL)-7,8-DIMETHOXY- 1,3-DIHYDRO-2H-3-BENZAZEPIN-2-ONE 3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one 7,8-Dimethoxy-3-(3-chloropropyl)-1,3-dihydro-2H-3-benzazepin-2-one 3-(3-chloropropyl)-7,8-diMethoxy-1H-benzo[d]azepin-2(3H)-one 8-Demethyl Ivabradine Intermediate（Ivabradine Impurity 8） (S)-3,3'-((((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)azanediyl)bis(propane-3,1-diyl))bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) 3-(3-Chloropropyl)-7,8-dimethoxy-2,3-dihydro-1H-benzoazepin-2-one -2-one 3-(3-Chloropropyl)-7,8-dimetho xy-1,3-dihydro-2H-3-benzazepin Ivabradine chloro Impurity 3-(3-chloropropy)-7,8-dimethoxy-1,3-dihydro-2H- benzo[d]azepin-2-one 85175-59-3