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Methyl phenoxyacetate

Methyl phenoxyacetate Structure
CAS No.
2065-23-8
Chemical Name:
Methyl phenoxyacetate
Synonyms
Methyl phenoxyacetat;METHYL PHENOXYACETATE;PHENOXY METHYL ACETATE;MethylPhenoxyacetate>Methyl phenoxyacetate,99%;Phenoxyacetic acid methyl;Methyl(ethyl)phenoxyacetate;phenoxy-aceticacimethylester;PHENOXYACETIC ACID METHYL ESTER;Acetic acid, phenoxy-, methyl ester
CBNumber:
CB0176981
Molecular Formula:
C9H10O3
Molecular Weight:
166.17
MOL File:
2065-23-8.mol
MSDS File:
SDS
Modify Date:
2023/9/12 17:26:57

Methyl phenoxyacetate Properties

Melting point 245 °C
Boiling point 243 °C (lit.)
Density 1.149 g/mL at 25 °C (lit.)
refractive index n20/D 1.514(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
Specific Gravity 1.149
color Colorless to Light orange to Yellow
InChIKey BZCKRPHEZOHHBK-UHFFFAOYSA-N
LogP 1.410
CAS DataBase Reference 2065-23-8(CAS DataBase Reference)
NIST Chemistry Reference Acetic acid, phenoxy-, methyl ester(2065-23-8)
EPA Substance Registry System Acetic acid, phenoxy-, methyl ester (2065-23-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
TSCA  T
HS Code  29189900
NFPA 704
1
0 0

Methyl phenoxyacetate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 275638 Methyl phenoxyacetate 99% 2065-23-8 10ML ₹6570.78 2022-06-14 Buy
TCI Chemicals (India) P0110 Methyl Phenoxyacetate min. 99.0 % 2065-23-8 25G ₹6100 2022-05-26 Buy
TCI Chemicals (India) P0110 Methyl Phenoxyacetate min. 99.0 % 2065-23-8 500G ₹86400 2022-05-26 Buy
Product number Packaging Price Buy
275638 10ML ₹6570.78 Buy
P0110 25G ₹6100 Buy
P0110 500G ₹86400 Buy

Methyl phenoxyacetate Chemical Properties,Uses,Production

Chemical Properties

Methyl phenoxyacetate, when the temperature ≥ 30°C is a clear colorless to slightly yellow liquid; at < 30°C is a white solid. It can be used as disinfectant or pharmaceutical intermediate or pesticide intermediate.

Uses

Methyl phenoxyacetate (MPOA) was used as an acylating agent in the synthesis of loracarbef, a carbacephalosporin antibiotic.

Preparation

synthesis of methyl phenoxyacetate: methyl bromoacetate (10 mL, 105.6 mmol) and phenol (9.9380 g, 105.6 mmol) were dissolved in 250 mL of acetone; K2CO3 (21.89 g, 158 mmol) and KI (5 g, 30 mmol) were added and the mixture heated to reflux with stirring overnight. The mixture was filtered and the resultant solution concentrated in vacuo. Deionized water (200 mL) was added. The reaction mixture was extracted with 50 mL ethyl acetate three times. The combined ethyl acetate layers were washed with brine, dried over MgSO4, and filtered. All ethyl acetate was removed in vacuo, resulting in a slightly yellow liquid (80% yield).

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