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NVP-BEZ 235

CAS No.: 915019-65-7

Chemical Name:: NVP-BEZ 235

Synonyms: 104794;CS-381;BEZ-235;RTB-101;Dactolisib;NVP-BEZ 235;BEZ235 0.6G;BEZ235, >=98%;NVP-BEZ235-NX;NVP-BEZ235-ANA

CBNumber:: CB01872365

Molecular Formula:: C30H23N5O

Molecular Weight:: 469.55

MOL File:: 915019-65-7.mol

MSDS File:: SDS

Modify Date:: 2024/11/19 15:53:33

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NVP-BEZ 235 Properties

Melting point	288-289°C
Boiling point	701.0±70.0 °C(Predicted)
Density	1.299
storage temp.	Refrigerator
solubility	Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75?C).
pka	6.41±0.20(Predicted)
form	White powder.
color	White or off-white
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
CAS DataBase Reference	915019-65-7

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

NFPA 704

	0
2		0

NVP-BEZ 235 Chemical Properties,Uses,Production

Chemical Properties

Light Beige Solid

Uses

Inhibitor of phosphatidylinositol 3-kinases, P13K and mTOR.

Definition

ChEBI: An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.

NVP-BEZ 235 Preparation Products And Raw materials

Raw materials

Preparation Products

NVP-BEZ 235 Suppliers

Global( 237)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	China	29730	60	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21628	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	33024	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29859	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	12162	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10244	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
ANHUI WITOP BIOTECH CO., LTD	58

NVP-BEZ 235 Spectrum

NVP-BEZ 235(915019-65-7)¹HNMR

915019-65-7(NVP-BEZ 235)Related Search:

4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester FGF-401 TAE226 (NVP-TAE226) NVP-LCQ195 NVP-TAE684

PENICILLIN V TRIMETHYLPHOSPHINE OXIDE TRIMETHYLSILOXYSILICATE 3-Methacryloxypropyltrimethoxysilane Everolimus

Selumetinib MK-2206 2HCl Pictilisib Trametinib Rapamycin

N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide NVP-BGT226 NVP-BSK805

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4-[2,3-Dihydro-3-Methyl-2-oxo-8-(quinolin-3-yl)-1H-iMidazo[4,5-c]quinolin-1-yl]-alpha,alpha-diMethylbenzeneacetonitrile BEZ-235 2-methyl-2-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)propanenitrile 2-Methyl-2-[3-Methyl-2-oxo-8-(3-quinolinyl)-1-iMidazo[4,5-c]quinolinyl]propanenitrile BEZ235 (NVP-BEZ235, Dactolisib) 2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl BEZ235 NVP-BEZ235(BEZ235) Dactolisib 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile BEZ235(NVP-BEZ235) NVP-BEZ 235 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile Benzeneacetonitrile, 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-.alpha.,.alpha.-dimethyl- 4-[2,3-Dihydro-3-Methyl-2-oxo-8-(3-quinolinyl)-1H-iMidazo[4,5-c]quinolin-1-yl]-α,α-diMethyl-benzeneacetonitrile NVP-BEZ235(BEZ235) BEZ235, >=98% BEZ-235 (Dactolisib) 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile Dactolisib 2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phe NVP-BEZ 235 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile 2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile BEZ235 0.6G BEZ235 (NVP-BEZ235) 104794 Dactolisib (BEZ235, NVP-BEZ235) CS-381 Dactolisib (BEZ235) NVP-BEZ235(Dactolisib NVP-BEZ 235;BEZ-235;BEZ 235;NVP-BEZ235;DACTOLISIB Benzeneacetonitrile, 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-α,α-dimethyl- NVP-BEZ 235 USP/EP/BP TIANFU-CHEM BEZ235 (NVP-BEZ235, Dactolisib) Dactolisib(NVP-BEZ 235) 4-2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo4,5-cquinolin-1-yl-.alpha.,.alpha.-dimethyl-benzeneacetonitrile NVP-BEZ235, PI3K and mTOR inhibitor NVP-BEZ235 Base NVP-BEZ235-ANA NVP-BEZ235-NX RTB-101 915019-65-7 5019-65-7 C30H23N5O Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators api Inhibitors Akt mTOR PI3K