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FGF-401

FGF-401 Structure
CAS No.
1708971-55-4
Chemical Name:
FGF-401
Synonyms
Roblitinib;0997;FGF-401;FGF 401;FGF-401;Roblitinib（FGF-401）;FGF401( Roblitinib);FGF-401 ISO 9001：2015 REACH;8-naphthyridine-1(2H)-carboxamide;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
CBNumber:
CB03166185
Molecular Formula:
C25H30N8O4
Molecular Weight:
506.56
MOL File:
1708971-55-4.mol
Modify Date:
2024/7/2 8:54:58
Request For Quotation

FGF-401 Properties

Boiling point 852.1±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
form A crystalline solid
pka 11.40±0.20(Predicted)
color White to off-white

FGF-401 Chemical Properties,Uses,Production

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401 Preparation Products And Raw materials

Raw materials

Preparation Products

FGF-401 Suppliers

Global( 108)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503259 +86-19930503259 China 18446 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
Zhejiang ZETian Fine Chemicals Co. LTD 58
BOC Sciences 58
career henan chemical co 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
Hebei Guanlang Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

FGF-401 Spectrum

FGF-401(1708971-55-4)1HNMR

1708971-55-4(FGF-401)Related Search:

Roxadustat 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester BEZ235 (NVP-BEZ235, Dactolisib)
8-naphthyridine-1(2H)-carboxamide 0997 FGF-401 N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide Roblitinib（FGF-401） FGF 401;FGF-401 N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide 1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]- FGF401( Roblitinib) FGF-401 ISO 9001：2015 REACH Roblitinib N-{5-cyano-4-[(2-methoxyethyl)amino]pyridin-2-yl}-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxamide 1708971-55-4 API