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KM 11060

KM 11060 Structure
CAS No.
774549-97-2
Chemical Name:
KM 11060
Synonyms
KM 11060;KM11060;KM-11060;CFTR-F508del Corrector, KM11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE;Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-;KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
CBNumber:
CB02446666
Molecular Formula:
C19H17Cl2N3O2S
Molecular Weight:
422.33
MOL File:
774549-97-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:57
Request For Quotation

KM 11060 Properties

storage temp. Store at RT
solubility Soluble to 100 mM in DMSO and to 10 mM in ethanol
form Powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  T
Risk Statements  25
Safety Statements  45
NFPA 704
0
2 0

KM 11060 Chemical Properties,Uses,Production

Uses

KM 11060 is a small molecular corrector of F508del CFTR trafficking, which has potential application in cystic fibrosis therapeutics.

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

KM 11060 Preparation Products And Raw materials

Raw materials

Preparation Products

KM 11060 Suppliers

Global( 76)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29824 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd +86-86-22-87899925 +86-8618522618860 China 694 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13183 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd 58
Henan Alfa Chemical Co., Ltd 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58

774549-97-2(KM 11060)Related Search:

TPP Benzyl alcohol 4-Chloroaniline Sulfenone 4'-Hydroxyacetophenone
Chlorobenzene 7-CHLORO-4-N,N-DIMETHYLAMINO-QUINOLINE 1-(4-Pyridyl)piperazine 4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE KM 11060
7-Chloro-4-piperazinoquinoline 4-(2-AMINOETHYL)AMINOQUINOLINE 7-CHLORO-4-(4-[(4-CHLORO-3-NITROPHENYL)SULFONYL]PIPERAZINO)QUINOLINE 4-(2-AMINOETHYL)AMINO-7-CHLOROQUINOLINE 4-PIPERAZIN-1-YL-QUINOLINE
1-(4-CHLORO-BENZENESULFONYL)-PIPERAZINE
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7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE 7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE KM 11060 CFTR-F508del Corrector, KM11060 KM11060;KM-11060 Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]- KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060 774549-97-2 api