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CYNARIN

CAS No.: 19870-46-3

Chemical Name:: CYNARIN

Synonyms: 19870-46-3 CYNARIN;1,3-Dicaffeoylquinic acid;Dicaffeoylquinic Acid, 1,5-;1,3-0-Dicaffeoylquinic acid;1,5-Dicaffeoylquinic acid-RM;1,5-di-O-Caffeoylquinic acid;1,3-Dicaffeoylquinic acid, 10 mM in DMSO;(1S,3R,4R,5R)-1,3-O-Dicaffeoylquinic acid;(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci

CBNumber:: CB02457303

Molecular Formula:: C25H24O12

Molecular Weight:: 516.45

MOL File:: 19870-46-3.mol

MSDS File:: SDS

Modify Date:: 2025/4/17 18:22:24

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CYNARIN Properties

Boiling point	819.9±65.0 °C(Predicted)
Density	1?+-.0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	soluble5mg/mL, clear, colorless to light yellow
form	Solid
pka	2.50±0.50(Predicted)
color	white to off-white
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319
Precautionary statements	P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
WGK Germany	3

CYNARIN price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	16917	1,5-Dicaffeoylquinic acid analytical standard	19870-46-3	5MG	₹54309.03	2022-06-14	Buy

Product number	Packaging	Price	Buy
16917	5MG	₹54309.03	Buy

CYNARIN Chemical Properties,Uses,Production

Description

1,5-Dicaffeoylquinic acid (1,5-DCQA) has been found in A. montana and is an HIV-1 integrase inhibitor and free radical scavenger. 1,5-DCQA inhibits HIV-1 integrase 3'' end processing, end joining, and disintegration with IC₅₀ values of 0.35, 0.56, and 0.84 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an ED₅₀value of 2 μg/ml. 1,5-DCQA (0.25-1 μM) reduces the level of free radicals released from human polymorphonuclear (PMN) cells stimulated by N-formyl-Met-Leu-Phe (fMLP; ) in a dose-dependent manner. It also dose-dependently increases cell survival and glutathione (GSH) levels and decreases reactive oxygen species (ROS) production and lactate dehydrogenase (LDH) release in an oxygen-glucose deprivation/reperfusion assay in rat cerebral astrocytes when used at concentrations ranging from 5 to 100 μM.

Uses

1,5-Dicaffeoylquinic Acid acts as an anti-hyperlipidemic agent. In addition, acts as a neuroprotective agent against amyloid-β toxicity in the treatement of Alzheimer’s.

CYNARIN Preparation Products And Raw materials

Raw materials

Preparation Products

CYNARIN Suppliers

Global( 131)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21628	55	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	China	3772	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10244	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24727	58	Inquiry
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	China	18137	58	Inquiry
TargetMol Chemicals Inc.		United States	38630	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Henan Tianfu Chemical Co.,Ltd.	55
Chengdu Biopurify Phytochemicals Ltd.	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
ANHUI WITOP BIOTECH CO., LTD	58
LEAP CHEM CO., LTD.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58

19870-46-3(CYNARIN)Related Search:

Cynarin Isochlorogenic Acid B Cryptochlorogenic acid CAFTARIC ACID 1-Caffeoylquinic acid

Isochlorogenic acid A Chlorogenic acid 1,3,5-Tricaffeoylquinic acid Isochlorogenic acid C 2,3,4,5-Tetracaffeoyl-D-Glucaric acid

Neochlorogenic acid

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1,3-Dicaffeoylquinic acid (1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid Dicaffeoylquinic Acid, 1,5- (1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid 1,5-di-O-Caffeoylquinic acid Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)- (1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci 19870-46-3 CYNARIN (1S,3R,4R,5R)-1,3-O-Dicaffeoylquinic acid CYNARIN|||Cyclohexanecarboxyli?c acid, 1,?3-?bis[[3-?(3,?4-?dihydroxyphenyl)?-?1-?oxo-?2-?propen-?1-?yl]?oxy]?-?4,?5-?dihydroxy-?, (1S,?3R,?4R,?5R)?-|||1,3-O-Dicaffeoylquinic acid|||1,5-Dicaffeoylquinic acid 1,5-Dicaffeoylquinic acid-RM 1,3-Dicaffeoylquinic acid, 10 mM in DMSO 1,3-0-Dicaffeoylquinic acid 19870-46-3 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract