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Cynarin

Cynarin Structure
CAS No.
30964-13-7
Chemical Name:
Cynarin
Synonyms
CYNARIN;CINARAN;Cinarin;1,5-DQA;CINARINE;Aids008522;Aids-008522;CYNARIN(ARTICHOKE);CYNARIN(ECHINACEA);Cynarin (Cynarine)
CBNumber:
CB8261807
Molecular Formula:
C25H24O12
Molecular Weight:
516.45
MOL File:
30964-13-7.mol
Modify Date:
2024/7/2 8:55:20

Cynarin Properties

Melting point 225-227°
alpha D25 -59° (c = 2 in methanol)
Boiling point 819.9±65.0 °C(Predicted)
Density 1?+-.0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility methanol: soluble5mg/mL, clear, light yellow to yellow
pka 2.58±0.50(Predicted)
form Solid
color faint yellow to yellow
Stability Hygroscopic
LogP 1.640 (est)
CAS DataBase Reference 30964-13-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
HS Code  29182900

Cynarin price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 91801 Cynarin analytical standard 30964-13-7 5MG ₹37194.7 2022-06-14 Buy
Product number Packaging Price Buy
91801 5MG ₹37194.7 Buy

Cynarin Chemical Properties,Uses,Production

Description

1,3-Dicaffeoylquinic acid is a polyphenol that has been found in C. scolymus. It decreases the expression and protein levels of inducible nitric oxide synthase (iNOS) when used at a concentration of 10 μM in human coronary artery smooth muscle cells (HCASMCs) treated with a cytokine mixture. 1,3-Dicaffeoylquinic acid decreases protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16F1 murine melanocytes. It inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates when used at a concentration of 25 μM. 1,3-Dicaffeoylquinic acid (20 and 40 μM) reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells compared to hyperlipidemic control cells.

Uses

Cynarin is used on MDR cells in anti-cancer therapy as an inhibitor of P-glycoprotein-mediated transport.

Cynarin Preparation Products And Raw materials

Global( 249)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Vital Herbs 08046067358 Delhi, India 36 58 Inquiry
Herbo Nutra +91-8048966502 Delhi, India 27 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12460 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503282 China 8828 58 Inquiry
1,5-DICAFFEOYLQUINIC ACID 1,3-DICAFFEOYLQUINIC ACID Dicaffeoylquinic Acid, 1,3- (1R,3R,4S,5R)-1,3-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-4,5-dihydroxycyclohexanecarboxylic acid CYNARIN(ECHINACEA) CYNARIN(ARTICHOKE) CYNARIN CINARINE CINARAN CYNARIN(ARTICHOKE)(1,5-DICAFFEOYLQUINIC ACID)(P) CYNARIN(ECHINACEA)(1,3-DICAFFEOYLQUINIC ACID)(AHP) (1R)-1,5α-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-3β,4α-dihydroxycyclohexane-1β-carboxylic acid (1R)-1β,3β-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4β,5α-dihydroxycyclohexanecarboxylic acid 1,3-O-Dicaffeoylquinic acid 1β,3β-Bis[3-(3,4-dihydroxyphenyl)propenoyloxy]-4β,5α-dihydroxycyclohexanecarboxylic acid 1,3-Di-o-caffeoylquinic acid Aids008522 Aids-008522 (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)propenoyl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid 1,5-Decaffeoyl quinic acid 1,3-Dicaffeoylquinic Acid (Artichoke Extract) Isochlorogenic acid A(3',5') Cinarin Cynarin Synonyms 1,3-Dicaffeoylquinic Acid (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid 1,5-DQA Cynarin, 98%, from Lonicera japonica 1,5-Dicaffeoylqunic acid (1S,3R,4R,5R)-1,3-bis[(E)-3-(3,4-dihydroxyphenyl)-1-oxoprop-2-enoxy]-4,5-dihydroxy-1-cyclohexanecarboxylic acid Cynarin (Cynarine) Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)- Anti-Hyperlipidemia 5% Cynarin Artichoke Extract 1,3-dicaffeoylquinicaci hot selling Cynarin 2-allyl-1,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo]oxy]-3,5-dihy... (1R,3R,4S,5R)-1,3-O-Dicaffeoylquinic acid(cynarin) Diuretic Cynarin 5% Synanthrin powder Jerusalem artichoke extract powder 1,5 dicaffecyl-verlinic acid 30964-13-7 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract