Cynarin
![Cynarin Structure](CAS/GIF/30964-13-7.gif)
- CAS No.
- 30964-13-7
- Chemical Name:
- Cynarin
- Synonyms
- CYNARIN;CINARAN;Cinarin;1,5-DQA;CINARINE;Aids008522;Aids-008522;CYNARIN(ARTICHOKE);CYNARIN(ECHINACEA);Cynarin (Cynarine)
- CBNumber:
- CB8261807
- Molecular Formula:
- C25H24O12
- Molecular Weight:
- 516.45
- MOL File:
- 30964-13-7.mol
- Modify Date:
- 2024/7/2 8:55:20
Melting point | 225-227° |
---|---|
alpha | D25 -59° (c = 2 in methanol) |
Boiling point | 819.9±65.0 °C(Predicted) |
Density | 1?+-.0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | methanol: soluble5mg/mL, clear, light yellow to yellow |
pka | 2.58±0.50(Predicted) |
form | Solid |
color | faint yellow to yellow |
Stability | Hygroscopic |
LogP | 1.640 (est) |
CAS DataBase Reference | 30964-13-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29182900 |
Cynarin Chemical Properties,Uses,Production
Description
1,3-Dicaffeoylquinic acid is a polyphenol that has been found in C. scolymus. It decreases the expression and protein levels of inducible nitric oxide synthase (iNOS) when used at a concentration of 10 μM in human coronary artery smooth muscle cells (HCASMCs) treated with a cytokine mixture. 1,3-Dicaffeoylquinic acid decreases protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16F1 murine melanocytes. It inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates when used at a concentration of 25 μM. 1,3-Dicaffeoylquinic acid (20 and 40 μM) reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells compared to hyperlipidemic control cells.
Uses
Cynarin is used on MDR cells in anti-cancer therapy as an inhibitor of P-glycoprotein-mediated transport.
Cynarin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Vital Herbs | 08046067358 | Delhi, India | 36 | 58 | Inquiry |
Herbo Nutra | +91-8048966502 | Delhi, India | 27 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12460 | 58 | Inquiry |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8828 | 58 | Inquiry |
30964-13-7(Cynarin)Related Search:
1of4
chevron_right