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Chlorogenic acid

Chlorogenic acid Structure
CAS No.
327-97-9
Chemical Name:
Chlorogenic acid
Synonyms
CAFFEOYLQUINIC ACID;Heriguard;3-CAFFEOYLQUINIC ACID;3-O-CAFFEOYLQUINIC ACID;Chlorogenic;ISOCHLOROGENIC ACID;CHLOROGENID ACID;CHLOROGENIC ACIDS;(1R,3R,4S,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexane-1-carboxylic acid;Buthotoxin
CBNumber:
CB2478906
Molecular Formula:
C16H18O9
Molecular Weight:
354.31
MOL File:
327-97-9.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43

Chlorogenic acid Properties

Melting point 210 °C (dec.) (lit.)
Boiling point 407.55°C (rough estimate)
alpha -36 º (c=1, H2O)
Density 1.3594 (rough estimate)
refractive index -37 ° (C=1, H2O)
storage temp. 2-8°C
solubility Soluble in ethanol and acetone.
form Powder, Crystals, Needles and/or Chunks
pka 3.91±0.50(Predicted)
color White to almost white
Water Solubility SOLUBLE IN HOT WATER
Merck 14,2142
InChIKey CWVRJTMFETXNAD-JUHZACGLSA-N
LogP -0.356 (est)
CAS DataBase Reference 327-97-9(CAS DataBase Reference)
EPA Substance Registry System Chlorogenic acid (327-97-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  68
Safety Statements  24/25
WGK Germany  3
RTECS  GU8480000
Hazard Note  Irritant
HS Code  29182900
Toxicity LDLo intraperitoneal in rat: 4gm/kg
NFPA 704
0
2 0

Chlorogenic acid price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C3878 Chlorogenic acid ≥95% (titration) 327-97-9 250MG ₹2749.55 2022-06-14 Buy
Sigma-Aldrich(India) C3878 Chlorogenic acid ≥95% (titration) 327-97-9 1G ₹8281.13 2022-06-14 Buy
Sigma-Aldrich(India) PHR2202 Chlorogenic Acid Pharmaceutical Secondary Standard; Certified Reference Material 327-97-9 100MG ₹18380.85 2022-06-14 Buy
Sigma-Aldrich(India) C3878 Chlorogenic acid ≥95% (titration) 327-97-9 5G ₹31251.78 2022-06-14 Buy
ALFA India ALF-J60457-MD Chlorogenic acid 327-97-9 250mg ₹2264 2022-05-26 Buy
Product number Packaging Price Buy
C3878 250MG ₹2749.55 Buy
C3878 1G ₹8281.13 Buy
PHR2202 100MG ₹18380.85 Buy
C3878 5G ₹31251.78 Buy
ALF-J60457-MD 250mg ₹2264 Buy

Chlorogenic acid Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellowish-beige powder

Uses

A major component of green coffee the extracts of which promote weight loss in overweight and obese people. Chlorogenic Acid is an important intermediate in lignin biosynthesis. Chlorogenic Acid is an antioxidant and an inhibitor of the tumor promoting activity of phorbol ester. It has protective effect against streptozotocin-nicotinamide generated oxidative stress induced diabetes and may also pr otect against cardiovascular disease.

General Description

Chlorogenic acid is a bioactive polyphenolic compound mainly found in many plants, such as coffee. It is a potent neuroprotectant and also possesses antiviral, antifungal, antioxidant and antitumor properties. CGA may also be involved in regulating glucose and lipid metabolism and improving insulin sensitivity.

Purification Methods

Crystallise the acid from water and dry it at 110o. [Beilstein 10 H 537, 10 I 271, 10 II 378, 10 III 2408, 10 IV 2259.]

Chlorogenic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorogenic acid, 98%, predoMinantly trans, froM coffee seeds Igasuric acid Chlorogenic acid ( green coffe bean extract) Chlorogenil acid Chlorogenic ac Chlorogenic acid Synonyms green coffe bean extract Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-, (1S,3R,4R,5R)- Chlorogenic acid (1S,3R,4R,5R)-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid Chlorogenic acid (98%HPLC) Chlorogenic acid >=95% (titration) 3-CAFFEOLYQUINICACID Chlorogenic Acid Hydrate Chlorogenic acid, 99%, predominantly trans, from coffee seeds [1S,4R,5R,(-)]-3β-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid 1,4α,5α-Trihydroxy-3β-[3-(3,4-dihydroxyphenyl)acryloyloxy]cyclohexane-1β-carboxylic acid Honegsukle Flowers Extract 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate) 3-(3,4-Dihydroxycinnamoyl)quinic Acid CHLOROGENIC ACID extrapure Chlorogenic acid,3-Caffeoylquinic acid Chlorogenic Acid (50 mg) Chlorogenic Acid (50 mg)F0C4200.97mg/mg(ai) Buthus martensii Karsch .p.e Chlorogenic acid ,98% Chlorogenic acid (Honeysuckle Flower P.E.) Chlorogenic acid (froM EucoMMia Bark) Eucommia Leaf Extract-- chlorogenic acid eucommin leaf extract 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate) 3-(3,4-Dihydroxycinnamoyl)quinic Acid 3-O-Caffeoylquinic acid CHLOROGENIC ACID, TRANS CHLOROGENIC ACID HELIANTHIC ACID CAFFEOLYQUINIC ACID CAFFETANNIC ACID CAFFEYLQUINIC ACID (1s,3r,4r,5r)-3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid 3-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL]OXY] 1,4,5-TRIHYDROXYCYCLOHEXANECARBOXYLIC ACID 3-(3,4-DIHYDROXYCINNAMOYL)-D(-)-QUINIC ACID 3-(3,4-DIHYDROXYCINNAMOYL)QUINIC ACID 1,3,4,5-TETRAHYDROXY-CYCLOHEXANECARBOXYLIC ACID 3-[3,4-DIHYDROXYCINNAMATE] 5-O-(3,4-Dihydroxycinnamoyl)-L-quinic acid 5-(3,4-DIHYDROXYCINNAMOYL)-D-(-)-QUINIC ACID 3R-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL]OXYL]-1S,4R,5R-TRIHYROXY-CYCLOHEXANECARBOXYLIC ACID 3-O-(3,4-DIHYDROXYCINNAMOYL)-D-QUINIC ACID NSC 407296 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-cyclohexanecarboxylicaci Chlorogenic acid, predominantly trans, from coffee seeds, 99% Cyclohexanecarboxylic acid, 3-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyloxy-1,4,5-trihydroxy-, (1S,3R,4R,5R)- chlorogenic acid (natural) CHLOROGENIC ACID PLANT CELLCULTURE TESTE D CHLOROGENIC ACID CRYSTALLINE CHLOROGENIC ACID, PREDOMINANTLY TRANS ChlorogenicAcid(EucommiaUlmoidesOliverPe)20%ByHplc 3-[3-C[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENY1]OXY]1,4,5-TRIHYDROXY-,[1S-(1α,3β,4α,5α)]- 5-trihydroxy-,(1s-(1-alpha,3-beta,4-alpha,5-alpha))-4 CYCOLOHEXANECABOXYLIOACID Chlorogenic acid (froM Flos lonicerae) NSC 70861 (1S,3R,4R,5R)-3-[(E)-3-(3,4-DIHYDROXY-PHENYL)-ACRYLOYLOXY]-1,4, 5-TRIHYDROXYCYCLOHEXANECARBOXYLIC ACID