ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Angiogenesis >HIF inhibitor >L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

CAS No.: 685898-44-6

Chemical Name:: L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

Synonyms: CS-1467;PX-478 HCl;PX478 2HCl;ALKN004012;PX 478 DISCONTINUED;PX-478 dihydrochloride;4-[Bis(2-chloroethyl)oxidoamino]-L-phenylalanine dihydrochloride;4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine,hydrochloride (1:2);L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1;Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

CBNumber:: CB02628046

Molecular Formula:: C13H19Cl3N2O3

Molecular Weight:: 357.66

MOL File:: 685898-44-6.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:54:57

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L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) Properties

storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	≥19.7 mg/mL in DMSO; ≥50 mg/mL in H2O; ≥8.42 mg/mL in EtOH
form	Powder
color	Off-white to yellow
CAS DataBase Reference	685898-44-6

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

NFPA 704

	0
2		0

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) Chemical Properties,Uses,Production

Uses

PX 478 is a HIF-1α inhibitor that may be used in cancer therapy for treatment of solid tumors. PX478 has also been shown to suppress high-fat-diet (HFD)-induced HIFα activation in adipose tissue in mice and therefore may be used to ameliorate adipose tissue dysfunction.

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) Suppliers

Global( 76)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	12962	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
Zhengzhou Alfa Chemical Co.,Ltd	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) Spectrum

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)(685898-44-6)MS

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L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) PX-478 dihydrochloride PX478 2HCl 4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine,hydrochloride (1:2) PX-478 HCl Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) 4-[Bis(2-chloroethyl)oxidoamino]-L-phenylalanine dihydrochloride (S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)aniline oxide dihydrochloride PX-478; L-PHENYLALANINE; 4-[BIS(2-CHLOROETHYL)OXIDOAMINO]-; DIHYDROCHLORIDE; L-PHENYLALANINE; 4-[BIS(2-CHLOROETHYL)OXIDOAMINO]-; HYDROCHLORIDE (1:2). CS-1467 L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1 PX 478 DISCONTINUED (S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamine oxide dihydrochloride ALKN004012 Inhibitor,Autophagy,HIFs,inhibit,PX-478,PX 478,HIF-PH,HIF/HIF Prolyl-Hydroxylase,PX478,Hypoxia-inducible factors 685898-44-6 C13H18Cl2N2O32HCl C13H20Cl4N2O3