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2,4,5-TRIFLUOROBENZYL CHLORIDE

2,4,5-TRIFLUOROBENZYL CHLORIDE Structure
CAS No.
243139-71-1
Chemical Name:
2,4,5-TRIFLUOROBENZYL CHLORIDE
Synonyms
Sitagliptin Impurity 70;2,4,5-TRIFLUOROBENZYL CHORIDE;2,4,5-TRIFLUOROBENZYL CHLORIDE;alpha-Chloro-2,4,5-trifluorotoluene;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
CBNumber:
CB0361981
Molecular Formula:
C7H4ClF3
Molecular Weight:
180.55
MOL File:
243139-71-1.mol
MSDS File:
SDS
Modify Date:
2023/8/17 18:11:45

2,4,5-TRIFLUOROBENZYL CHLORIDE Properties

Boiling point 175℃
Density 1,689 g/cm3
refractive index 1.5050
Flash point 65°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color Colorless to Almost colorless
InChI InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
InChIKey JMXPOOVDUVHJRO-UHFFFAOYSA-N
SMILES C1(CCl)=CC(F)=C(F)C=C1F
CAS DataBase Reference 243139-71-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H227-H290-H314-H318
Precautionary statements  P210e-P260h-P303+P361+P353-P305+P351+P338-P501a-P210-P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P403+P235-P405-P406-P501
Hazard Codes  C,Xn
Risk Statements  34-36/37/38-20/21/22
Safety Statements  26-36/37/39-36
RIDADR  3265
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  2903998090
NFPA 704
2
3 0

2,4,5-TRIFLUOROBENZYL CHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) T2889 2,4,5-Trifluorobenzyl Chloride min. 98.0 % 243139-71-1 1G ₹5000 2022-05-26 Buy
TCI Chemicals (India) T2889 2,4,5-Trifluorobenzyl Chloride min. 98.0 % 243139-71-1 5G ₹19800 2022-05-26 Buy
Product number Packaging Price Buy
T2889 1G ₹5000 Buy
T2889 5G ₹19800 Buy

2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

Colorless to Almost colorless clear liquid.

Uses

2,4,5-Trifluorobenzyl chloride is a useful research chemical.

Uses

2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in glucagon to improve control of blood sugar used for the treatment of type 1 diabetes, 79% of the dose excreted in the urine.

Synthesis

On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride.

2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2,4,5-TRIFLUOROBENZYL CHLORIDE Suppliers

Global( 165)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
VSK LIFE SCIENCES PRIVATE LIMITED +91 7995529789 Hyderabad, India 220 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
VASIN BIO LIFE SCIENCES PVT LTD 9491644688 Hyderabad, India 2096 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Shanghai Qianyi New Material Co., Ltd. +8618083322317 China 878 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +8613288715578 China 12456 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
2,4,5-TRIFLUOROBENZYL CHLORIDE 2,4,5-TRIFLUOROBENZYL CHORIDE Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI) 1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene Sitagliptin Impurity 70 Benzene, 1-(chloromethyl)-2,4,5-trifluoro- alpha-Chloro-2,4,5-trifluorotoluene 243139-71-1 C7H4CIF3 Fluorine series HALOMETYL Miscellaneous