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Sitagliptin DeaMino IMpurity 1

Sitagliptin DeaMino IMpurity 1 Structure
CAS No.
1253056-18-6
Chemical Name:
Sitagliptin DeaMino IMpurity 1
Synonyms
Sitagliptin FP Impurity D;Impurity FP-D;Sitagliptin iMpurity S;Sitagliptin Impurity 01;Sitagliptin Impurity 05;Sitagliptin Impurity FP-D;Sitagliptin EP Impurity 13;Sitagliptin EP Impurity FP-D;Sitagliptin DeaMino IMpurity 1;Sitagliptin Steryl acetyl Analog
CBNumber:
CB22675695
Molecular Formula:
C16H12F6N4O
Molecular Weight:
390.28
MOL File:
1253056-18-6.mol
Modify Date:
2023/4/23 13:52:06
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Sitagliptin DeaMino IMpurity 1 Properties

Boiling point 517.5±60.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol
pka -0.06±0.20(Predicted)
form Solid
color Colourless to Pale Yellow Gel to Waxy
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Sitagliptin DeaMino IMpurity 1 Chemical Properties,Uses,Production

Uses

3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin DeaMino IMpurity 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Sitagliptin DeaMino IMpurity 1 Suppliers

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1253056-18-6(Sitagliptin DeaMino IMpurity 1)Related Search:

BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Sitagliptin Sitagliptin Defuoro IMpurity 3 tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)amino)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate 1,2,4-Triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, 6,7,10,11-tetrahydro-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]-
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin IMpurity
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Sitagliptin Impurity 34 Sitagliptin N-Phoshate IMpurity Sitagliptin impurity H HCl Sitagliptin Impurity 31
Sitagliptin phosphate Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid
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Sitagliptin DeaMino IMpurity 1 (2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (E)-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one Sitagliptin iMpurity S (E)-1-(3-(trifluoromethyl)-5,6-dihydro Sitagliptin impurity 8/Sitagliptin FP Impurity D/3-Desamino-2,3-Dehydro Sitagliptin/(2E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one 3-Desamino-2,3-dehydro Sitagliptin Sitagliptin Impurity FP-D Sitagliptin phenyl crotonyl analog Impurity FP-D Sitagliptin EP Impurity FP-D Sitagliptin USPPhenylcrotonyl Analog 2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2E)- Sitagliptin EP Impurity 13 Sitagliptin Impurity 01 (E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity) Sitagliptin Steryl acetyl Analog SITAGLIPTIN STYRYLACETYL IMPURITY Sitagliptin Phenylcrotonyl Analog (Sitagliptin FP Impurity D/ 3-Desamino-2,3-Dehydro Sitagliptin) Sitagliptin Phenylcrotonyl Analog/Sitagliptin FP Impurity D Sitagliptin Tablets EP Impurity FP-D Sitagliptin FP Impurity D Sitagliptin Impurity 17 (Sitagliptin Tablets EP Impurity FP-D) Sitagliptin Impurity 05 1253056-18-6