ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and proteins >FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Structure
CAS No.
1013883-02-7
Chemical Name:
FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
Synonyms
Fmoc-phe(2-Ae-Boc)-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-phenylalanine;FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE;N-Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl 4-[2-((Tert-Butoxy)Carbonyl amino)ethoxy]-L-Phenylalanine;O-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine;L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-((tert-butoxycarbonyl)amino)ethoxy)phenyl)propanoic acid;(2S)-3-[4-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CBNumber:
CB0432276
Molecular Formula:
C31H34N2O7
Molecular Weight:
546.61
MOL File:
Mol file
Modify Date:
2023/5/4 15:15:58

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Properties

Boiling point 759.1±60.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
pka 2.96±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS05
Signal word  Danger
Hazard statements  H315-H335-H318
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310
HazardClass  IRRITANT

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Chemical Properties,Uses,Production

Uses

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

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Add O-[2-[[tert-butoxycarbonyl]amino]ethyl]-L-tyrosine (3.24g, 10mmol) in a 100mL three-necked flask equipped with magnetic stirring and a thermometer, with a mass concentration of 5 · 5% 21.2g of sodium carbonate aqueous solution, 20mL of 9-fluorenylmethyl-N-succinimidyl carbonate (3.37g, 10mmol) in tetrahydrofuran solution was added dropwise at room temperature, after the addition, the amidation reaction was carried out at room temperature, monitored by TLC To the end of the reaction. Concentrated to remove part of the solvent, acidified with 2N hydrochloric acid to pH 6~7, extracted with ethyl acetate, washed with saturated brine, concentrated, beaten with petroleum ether, filtered and dried to obtain a white solid O-alkyl-N-[ Fluorenylmethyloxycarbonyl]-L-tyrosine is 4.68g, the yield is 85.7%, the HPLC purity is 99.8%, and the ee value is 99.8%.

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 71)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
Chengdu Aslee Biopharmaceuticals, Inc. 28-85305008 CHINA 964 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH N-Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine O-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine Fmoc-4-[2-(Boc-amino)ethoxy]-phenylalanine (9H-Fluoren-9-yl)MethOxy]Carbonyl 4-[2-((Tert-Butoxy)Carbonyl amino)ethoxy]-L-Phenylalanine Fmoc-phe(2-Ae-Boc)-OH (2S)-3-[4-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-((tert-butoxycarbonyl)amino)ethoxy)phenyl)propanoic acid 1013883-02-7 peptide