ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Asparagine derivatives >Fmoc-Asn(Trt)-OH
Fmoc-Asn(Trt)-OH
- CAS No.
- 132388-59-1
- Chemical Name:
- Fmoc-Asn(Trt)-OH
- Synonyms
- FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
- CBNumber:
- CB4331632
- Molecular Formula:
- C38H32N2O5
- Molecular Weight:
- 596.67
- MOL File:
- 132388-59-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/12/7 16:07:34
| Melting point | 201-204 °C(lit.) |
|---|---|
| alpha | -16 º (c=1, MeOH) |
| Boiling point | 858.1±65.0 °C(Predicted) |
| Density | 1.271±0.06 g/cm3(Predicted) |
| refractive index | -19 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | <0.00005g/l |
| pka | 3.79±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | [α]20/D 15.0±1°, c = 1% in methanol |
| BRN | 4343823 |
| InChIKey | KJYAFJQCGPUXJY-UUWRZZSWSA-N |
| SMILES | C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| CAS DataBase Reference | 132388-59-1(CAS DataBase Reference) |
Fmoc-Asn(Trt)-OH price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 25G | ₹5800.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 100G | ₹13940 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 250G | ₹29660.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 47672 | Fmoc-Asn(Trt)-OH ≥97.0% | 132388-59-1 | 5G | ₹7155.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 47672 | Fmoc-Asn(Trt)-OH ≥97.0% | 132388-59-1 | 25G | ₹10640.98 | 2022-06-14 | Buy |
Fmoc-Asn(Trt)-OH Chemical Properties,Uses,Production
Description
Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.
Chemical Properties
white crystal powde
Uses
Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
Preparation
Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.
Fmoc-Asn(Trt)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 439)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Globe Chemie | 08048372441Ext 581 | Pune, India | 101 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Globe Chemie | +91 (20) 3230-9500 | New Delhi, India | 294 | 50 | Inquiry |
| Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 | China | 163 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| JSK Chemicals | 58 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| Globe Chemie | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Globe Chemie | 50 |
| Lanxi Xingnuo Import and Export Trading Co., Ltd | 58 |
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FMOC-ASPARAGINE(TRT)
FMOC-ASN(XAN)-OH
FMOC-L-ASN(TRITYL)
FMOC-L-ASPARGINE(TRITYL)
FMOC-L-ASPARAGINE(TRITYL)
FMOC-L-ASPARAGINE (TRT)
FMOC-N-GAMMA-XANTHYL-L-ASPARAGINE
Nalpha-fluorenylmethoxycarbonyl-Ngamma-trityl-L-asparagine
Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine, Nα-Fmoc-Nγ-trityl-L-asparagine
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Fmoc-Asn(Trt)-OH
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(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-4-oxo-4-(tritylaMino)butanoic acid
FMoc-Asn(Tre)
Fmoc-Asn(Trt)-OH >=97.0% (sum of enantiomers, HPLC)
Fmoc-Asn(Trt)-OH(CAS:132388-59-1)
FMOC-NG-TRITYL-L-ASPARAGINE
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FMOC-N-TRITYL-L-ASPARAGINE
FMOC-N-BETA-TRITYL-L-ASPARAGINE
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Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine
na-fmoc-N-gamma-trityl-L-asparagine
N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit
N-α-Fmoc-N-γ-trityl-L-asparagine
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-&
FMOC-N-TRITYL-L-ASPARAGINE 97+%
N-FMOC-N4-TRITYL-L-ASPARAGINE
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N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-(TRIPHENYLMETHYL)-L-ASPARAGINE
N-.ALPHA.-FMOC-N-.GAMMA.-XANTHYL-L-ASPARAGINE
N-α-Fmoc-β-trityl-L-asparagine
L-Asparagine N-β-Trityl-15N2-N-α-FMOC
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Nα-Fmoc-Nγ-trityl-L-asparagine≥ 99.7% (HPLC, Chiral purity)
N-FMOC-L-ASN(TRT)-OH
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Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nγ-trityl-L-asparagine>