TUBERCIDIN
![TUBERCIDIN Structure](CAS/GIF/69-33-0.gif)
- CAS No.
- 69-33-0
- Chemical Name:
- TUBERCIDIN
- Synonyms
- (2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;b120121;u-10071;CS-2599;nsc56408;ski26996;Aids051983;TUBERCIDIN;7-Deaza-Ar;7-Deaza-rA
- CBNumber:
- CB0461137
- Molecular Formula:
- C11H14N4O4
- Molecular Weight:
- 266.25
- MOL File:
- 69-33-0.mol
- Modify Date:
- 2023/6/8 9:02:16
Melting point | 247-248 °C (decomp)(Solv: water (7732-18-5)) |
---|---|
alpha | D17 -67° (50% acetic acid) |
Boiling point | 409.46°C (rough estimate) |
Density | 1.2896 (rough estimate) |
refractive index | 1.8340 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Soluble in DMSO |
form | powder |
pka | 12.44±0.70(Predicted) |
color | off-white |
Merck | 13,9875 |
BRN | 38498 |
Stability | Hygroscopic |
InChIKey | HDZZVAMISRMYHH-UIRWVKCDSA-N |
CAS DataBase Reference | 69-33-0 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H300 | |||||||||
Precautionary statements | P264-P301+P310 | |||||||||
Hazard Codes | T+ | |||||||||
Risk Statements | 28 | |||||||||
Safety Statements | 36/37/39-45 | |||||||||
RIDADR | UN 3462 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UY8870000 | |||||||||
F | 10 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | II | |||||||||
HS Code | 29419090 | |||||||||
Toxicity | LD50 i.v. in mice: 45 mg/kg (Anzai) | |||||||||
NFPA 704 |
|
TUBERCIDIN price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T0642 | Tubercidin from Streptomyces tubercidicus, ~95% | 69-33-0 | 10MG | ₹12470.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T0642 | Tubercidin from Streptomyces tubercidicus, ~95% | 69-33-0 | 50MG | ₹46287.7 | 2022-06-14 | Buy |
TUBERCIDIN Chemical Properties,Uses,Production
Chemical Properties
White crystal
Uses
Tubercidin is a nucleoside metabolite first isolated from Streptomyces tubericidus. Tubercidin, like other nucleosides, is a broad spectrum, potent chemotherapeutic agent active against viruses, bacteria, fungi, protozoans and tumours. Tubercidin acts at a diverse range of sites, such as RNA processing, nucleic acid and protein synthesis, and acts as a nucleoside mimic of adenosine.
Definition
ChEBI: An N-glycosylpyrrolopyrimidine that is adenosine in which the in the 5-membered ring that is not attached to the ribose moiety is replaced by a carbon. Tubercidin is produced in the culture broth of Streptomyces tubericidus.
Purification Methods
7-Deazaadenosine forms needles from hot H2O. It is soluble in H2O (0.33%), MeOH (0.5%) and EtOH (0.05%). It has UV max at 270nm ( 12,100) in 0.001N NaOH. The picrate has m 229-231o(dec). [Tolman et al. J Am Chem Soc 91 2102 1969, Mizuno et al. J Org Chem 28 3329 1963, IR: Anzai et al. J Antibiot (Japan) [9] 10 201 1957, Beilstein 26 IV 1117.]
TUBERCIDIN Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 | China | 1640 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | China | 117 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5999 | 58 | Inquiry |
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