ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleoside Intermediates >5-IODOTUBERCIDIN
5-IODOTUBERCIDIN
- CAS No.
- 24386-93-4
- Chemical Name:
- 5-IODOTUBERCIDIN
- Synonyms
- ITU;5-ITu;CS-824;NSC 113939;IODOTUBERCIDIN;7-I-7-Deaza-Ar;5-IODOTUBERCIDIN;5-IODOTUBERICIDIN;Iodotubercidin,Itu;5-Iodo-Tubercidine
- CBNumber:
- CB1280221
- Molecular Formula:
- C11H13IN4O4
- Molecular Weight:
- 392.15
- MOL File:
- 24386-93-4.mol
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 216-217°C dec. |
|---|---|
| Boiling point | 701.5±60.0 °C(Predicted) |
| Density | 2.49±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | 0.1 M HCl: 0.7 mg/mL |
| form | solid |
| pka | 12.33±0.70(Predicted) |
| color | tan |
| Stability | Store tightly sealed at 4°C; Light Sensitive |
| InChIKey | WHSIXKUPQCKWBY-IOSLPCCCSA-N |
| CAS DataBase Reference | 24386-93-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
| HS Code | 29349990 |
5-IODOTUBERCIDIN price More Price(2)
5-IODOTUBERCIDIN Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
5-Iodotubercidin has been used for the inhibition of retinoblastoma cells, astroglial cultures and for the inhibition of adenosine kinase in human umbilical vein endothelial cells (HUVECs).
General Description
solubility: 10 mg/mL in DMSO
Biological Activity
Potent adenosine kinase inhibitor (IC 50 = 26 nM) and nucleoside transporter inhibitor (IC 50 values are 7, 15 and < 25 nM for inhibition of [ 3 H]-uridine, [ 3 H]-formycin B and [ 3 H]-adenosine uptake respectively). Strongly stimulates glycogen synthesis in hepatocytes via activation of glycogen synthase. Also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC (IC 50 values are 0.4, 3.5, 5-10, 5-10, 10.9 and 27.7 μ M respectively).
5-IODOTUBERCIDIN Preparation Products And Raw materials
Raw materials
α-D-Ribofuranosyl chloride, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-
7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-5-iodo-7-b-D-ribofuranosyl-
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
5-O-TERT-BUTYLDIMETHYLSILYL-2,3-O-ISOPROPYLIDENE-D-RIBOFURANOSE
7H-Pyrrolo[2,3-d]pyriMidine, 4-chloro-5-iodo-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-
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Global( 171)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | China | 1807 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | China | 117 | 58 | Inquiry |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | China | 321 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | China | 138 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
24386-93-4(5-IODOTUBERCIDIN)Related Search:
7-IODO-7-DEAZAADENOSINE
5-IODOTUBERCIDIN
5-IODOTUBERICIDIN
4-AMINO-5-IODO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
IODOTUBERCIDIN
ITU
Iodotubercidin,Itu
4-Amino-5-iodo-7-(b-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
4-amino-5-iodo-7-(β-d-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
5-IODOTUBERCIDIN 98+%
iodotubercidin, 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
7-Deaza-7-iodoadenosine
5-Iodotubercidin (or 7-Deaza-7-iodoadenosine)
3-d]pyriMidin-7-yl)-tetrahydro-5-(hydroxyMethyl)furan-3
5R)-2-(4-aMino-5-iodo-7H-pyrrolo[2
NSC 113939
5-ITu
7H-Pyrrolo[2,3-d]pyriMidin-4-aMine,5-iodo-7-b-D-ribofuranosyl-
7-Iodo-7-deazaadenosine, 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
(2R,3R,4S,5R)-2-(4-amino-5-iodo-5H-pyrrolo[2,3-d]pyrimidin-7(6H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
7-I-7-Deaza-Ar
(2S,3S,4R,5S)-2-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
(2R,3R,4S,5R)-2-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
5-IODOTUBERCIDIN USP/EP/BP
4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, 7-Iodo-tubercidin, 7-deaza-7-iodoadenosine
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-β-D-ribofuranosyl-
5-Iodotubercidin (NSC 113939)
2-{4-AMINO-5-IODOPYRROLO[2,3-D]PYRIMIDIN-7-YL}-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL
CS-824
5-Iodo-Tubercidine
3-d]pyrimidin-4- amine
5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2
4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
7-Iodo-tubercidin,7-Deaza-7-iodoadenosine,Adenosine kinase inhibitor, Protein kinase inhibitor and activator, nucleoside transporters inhibitor
5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
24386-93-4
C11H13IN4O4
Bases & Related Reagents
Inhibitors
Nucleotides
Protein Kinase Inhibitors and Activators
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