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API-2

API-2 Structure
CAS No.
35943-35-2
Chemical Name:
API-2
Synonyms
TCN;IAP1;MIHC;MYHL;BBMI;API-2;BIRC3;RNF49;MYO1A;DFNA48
CBNumber:
CB3270000
Molecular Formula:
C13H16N6O4
Molecular Weight:
320.3
MOL File:
35943-35-2.mol
MSDS File:
SDS
Modify Date:
2023/8/7 22:27:18

API-2 Properties

Melting point 207 °C (decomp)
Boiling point 459.21°C (rough estimate)
Density 1.2633 (rough estimate)
refractive index 1.7000 (estimate)
storage temp. Store at RT
solubility DMSO: >10mg/mL
form powder
pka 12.35±0.70(Predicted)
color tan
InChIKey HOGVTUZUJGHKPL-HTVVRFAVSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
WGK Germany  3
RTECS  RY8455000

API-2 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T3830 Triciribine hydrate ≥97% (HPLC) 35943-35-2 5MG ₹27679.53 2022-06-14 Buy
Sigma-Aldrich(India) T3830 Triciribine hydrate ≥97% (HPLC) 35943-35-2 25MG ₹112699.08 2022-06-14 Buy
Sigma-Aldrich(India) SAB1303874 ANTI-MYO1A (CENTER S291) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution 35943-35-2 400μL ₹47796.6 2022-06-14 Buy
Sigma-Aldrich(India) 124038 InSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem The InSolution Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibi 35943-35-2 2MG ₹28660 2022-06-14 Buy
Product number Packaging Price Buy
T3830 5MG ₹27679.53 Buy
T3830 25MG ₹112699.08 Buy
SAB1303874 400μL ₹47796.6 Buy
124038 2MG ₹28660 Buy

API-2 Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Biological Activity

Selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways. Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3 β and AFX. In vitro, induces apoptosis and growth arrest preferentially in human cancer cells with elevated levels of Akt. In mice, potently and selectively inhibits growth of Akt-overexpressing tumors. Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2.

API-2 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 155)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Wuhan Haorong Biotechnology Co.,ltd +86-18565342920; +8618565342920 China 293 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 12962 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Wuhan Nutra Biotechnology Co.,Ltd +8617786394783 China 300 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry

API-2 Spectrum

API-2 6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE AKT/PKB SIGNALING INHIBITOR-2 AKT INHIBITOR V 1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE 1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura API-2 (Tricirbine) TRICIRIBINE NSC 154020 TCN 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine (1,4,5,6,8-Pentaazaacenaphthylen-3-aMine,1,5-dihydro-5-Methyl-1-b-D-ribofuranosyl-) 6-AMino-4-Methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyriMido[4,5-c]pyridazine (2R,3R,4S,5R)-2-(3-aMino-5-Methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol VD-0002 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine Triciribine Triciribine 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine Inhibitor V (1R,2S,3R,5R)-3-(3-Amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxymethyl)c InSolution? Akt Inhibitor V, Triciribine Triciribine hydrate ANTI-CIAP2 (BIRC3)(N-TERMINAL) antibody produced in rabbit BIRC3 IAP1 MIHC RNF49 ANTI-MYO1A (CENTER S291) antibody produced in rabbit Brush border myosin I MYHL Myosin-Ia Anti-MYO1A antibody produced in rabbit BBMI DFNA48 MYO1A Anti-Dfna48 Anti-Myhl Anti-Myosin ia Triciribine, >=98% 1,4,5,6,8-pentaazaacenaphthylene,3-amino-1,5-dihydro-5-methyl-1-beta-d-ribof 3-amine 3-amino-1,5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1,4,5,6,8-pentaazaacenap 4,5,6,8-pentaazaacenaphthylen-5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1 hthylene nosyl- pentaazacentopthylene uranosyl- TRICYCLIC NUCLEOSIDE CS-542 API-2; NSC 154020; TCN CS-690 Triciribine, NSC 154020, TCN InSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem Triciribine (NSC-154020) Triciribine, 98%, a DNA synthesis inhibitor Tricirbine 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl- API-2 USP/EP/BP Triciribine 13CD3