MITRAPHYLLINE

MITRAPHYLLINE Structure
CAS No.
509-80-8
Chemical Name:
MITRAPHYLLINE
Synonyms
Rubradinin;Rubradinine;Mitraphyllin;MITRAPHYLLINE;MITRAPHILLINE;Ajmalicine oxindole B;Methyl 19α-methyl-2-oxoformosanan-16-carboxylate;Uncaria,Mitraphylline,tomentosa,Inhibitor,inhibit;methyl -19alpha-methyl-2-oxoformosanan-16-carboxylate;19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
CBNumber:
CB0469380
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.43
MOL File:
509-80-8.mol
Modify Date:
2024/7/2 8:54:58

MITRAPHYLLINE Properties

Melting point 265~266℃
Boiling point 555.2±50.0 °C(Predicted)
Density 1.33
solubility DMF: 5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: slightly soluble
form A crystalline solid
pka 13.56±0.60(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
NFPA 704
0
4 0

MITRAPHYLLINE Chemical Properties,Uses,Production

Uses

Mitraphyllin is used in studies to evaluate isoniazid resistance and antibiotic activity potentiation in Mycobacterium using antibiotic combinations.

MITRAPHYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Ajmalicine oxindole B (1S,4aS,5aS,6R,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate (1'S,3R,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-Octahydro-1'-methyl-2-oxospiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid methyl ester Mitraphyllin Rubradinin Rubradinine MITRAPHILLINE MITRAPHYLLINE methyl -19alpha-methyl-2-oxoformosanan-16-carboxylate Methyl 19α-methyl-2-oxoformosanan-16-carboxylate Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aS,10'aR)- Spiro[3H-indole-3,6'(4'αH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylicacid, 1,2,5',5'α,7',8',10',10'α-octahydro-1'-methyl-2-oxo-, methyl ester,(1'S,3R,4'αS,5'αS,10'αR)- Uncaria,Mitraphylline,tomentosa,Inhibitor,inhibit 509-80-8 Miscellaneous Natural Products